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Rheumatology News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (24) Full Text Articles (287) Focus on Osteoporosis
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Use of Lipid-lowering Agents in Rheumatoid Arthritis: A Population-based Cohort Study The Journal of Rheumatology, May 11, 2013    Clinical Article
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2 The risk of gastrointestinal perforations in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the BSRBR-RA Annals of Rheumatic Diseases, May 11, 2013    Clinical Article

3 Treatment strategies for early rheumatoid arthritis Current Opinion in Rheumatology, May 11, 2013    Clinical Article

4 Kinase inhibitors: A new tool for the treatment of Rheumatoid Arthritis Clinical Immunology, May 11, 2013    Clinical Article

5 Thyroxin substitution and the risk of developing rheumatoid arthritis; results from the Swedish population-based EIRA study Annals of Rheumatic Diseases, May 11, 2013    Clinical Article

6 Do biologic drugs affect the need for and outcome of joint replacements in patients with rheumatoid arthritis- A register-based study Seminars in Arthritis and Rheumatism, May 11, 2013    Clinical Article

7 Rheumatoid arthritis in the elderly: recent advances in understanding the pathogenesis, risk factors, comorbidities and risk-benefit of treatments Aging Health, May 11, 2013    Review Article

8 Obesity among women may increase the risk of arthritis: observations from the Canadian Community Health Survey, 2007-2008 Rheumatology International, May 11, 2013    Clinical Article

9 New methods for determining comparative effectiveness in rheumatoid arthritis Current Opinion in Rheumatology, May 11, 2013    Clinical Article

10 Long-term treatment of rheumatoid arthritis with adalimumab Full Text Open Access Rheumatology: Research and Reviews, May 11, 2013    Clinical Article

11 Induced abortions in women with rheumatoid arthritis on methotrexate Arthritis Care & Research , May 11, 2013    Clinical Article

12 Newest clinical trial results with antitumor necrosis factor and nonantitumor necrosis factor biologics for rheumatoid arthritis Current Opinion in Rheumatology, May 11, 2013    Clinical Article

13 Biologic therapies and systemic bone loss in Rheumatoid Arthritis Autoimmunity Reviews, May 11, 2013    Clinical Article

14 Assessing subclinical synovitis in rheumatoid arthritis Arthritis & Rheumatism, May 11, 2013    Clinical Article

15 Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy Arthritis Research & Therapy, May 11, 2013    Review Article

16 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 27, 2013    Clinical Article

17 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 27, 2013    Clinical Article

18 Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis Annals of Rheumatic Diseases, April 27, 2013    Evidence Based Medicine    Review Article    Clinical Article

19 Clinical Response Within 12 Weeks as a Predictor of Future Low Disease Activity in Patients with Early RA: Results from the TEAR Trial The Journal of Rheumatology, April 27, 2013    Clinical Article

20 Longterm Effects of Rituximab on B Cell Counts and Autoantibody Production in Rheumatoid Arthritis: Use of High-sensitivity Flow Cytometry for More Sensitive Assessment of B Cell Depletion The Journal of Rheumatology, April 27, 2013    Clinical Article

21 Adalimumab: 8 years of experience in rheumatoid arthritis International Journal of Clinical Rheumatology, April 27, 2013    Clinical Article

22 Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case-control study Arthritis Research & Therapy, April 27, 2013    Clinical Article

23 Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies Annals of Rheumatic Diseases, April 27, 2013    Clinical Article

24 IL-32 with potential insights into rheumatoid arthritis Clinical Immunology, April 27, 2013    Review Article

25 The type I IFN signature as a biomarker of preclinical rheumatoid arthritis Annals of Rheumatic Diseases, April 27, 2013    Clinical Article

26 Effects of smoking on the clinical phenotype and response to treatment in rheumatoid arthritis International Journal of Clinical Rheumatology, April 27, 2013    Clinical Article

27 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 14, 2013    Clinical Article

28 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 14, 2013    Clinical Article

29 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Annals of Rheumatic Diseases, April 14, 2013    Clinical Article

30 Long-term therapeutic effects and safety of tacrolimus added to methotrexate in patients with rheumatoid arthritis Rheumatology International, April 14, 2013    Clinical Article

31 Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial Annals of Rheumatic Diseases, April 14, 2013    Clinical Article

32 Efficacy and Safety of Belimumab in Patients with Rheumatoid Arthritis: A Phase II, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study The Journal of Rheumatology, April 14, 2013    Clinical Article

33 Agreement between the das-crp assessed with 3 and 4 variables in patients with rheumatoid arthritis treated with biological agents in the daily clinic The Journal of Rheumatology, April 14, 2013    Clinical Article

34 Epidermal growth factor receptor (EGFR) as a therapeutic target in rheumatoid arthritis Clinical Rheumatology, April 14, 2013    Clinical Article

35 Anaemia may add information to standardised disease activity assessment to predict radiographic damage in rheumatoid arthritis: a prospective cohort study Annals of Rheumatic Diseases, April 14, 2013    Clinical Article

36 Cardiovascular Events Are Not Associated with MTHFR Polymorphisms, But Are Associated with Methotrexate Use and Traditional Risk Factors in US Veterans with Rheumatoid Arthritis The Journal of Rheumatology, April 14, 2013    Clinical Article

37 Remission in patients with active rheumatoid arthritis by tocilizumab treatment in routine clinical practice: results from 3 years of prospectively registered data Modern Rheumatology, April 14, 2013    Clinical Article

38 Metabolic profiling predicts response to anti-TNF therapy in patients with rheumatoid arthritis Arthritis & Rheumatism, April 14, 2013

39 Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial The Lancet, March 31, 2013    Clinical Article

40 The diagnostic utility of matrix metalloproteinase-3 and high-sensitivity C-reactive protein for predicting rheumatoid arthritis in anti-cyclic citrullinated peptide antibody-negative patients with recent-onset undifferentiated arthritis Rheumatology International, March 31, 2013    Clinical Article

41 Biologic disease-modifying anti-rheumatic drugs and the risk of non-vertebral osteoporotic fractures in patients with rheumatoid arthritis aged 50 years and over Osteoporosis International, March 31, 2013    Clinical Article

42 Anti-citrullinated protein antibodies (ACPA) in unaffected first degree relatives of rheumatoid arthritis patients Arthritis & Rheumatism, March 31, 2013

43 Detection, scoring and volume assessment of bone erosions by ultrasonography in rheumatoid arthritis: comparison with CT Annals of Rheumatic Diseases, March 31, 2013    Clinical Article

44 Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study Annals of Rheumatic Diseases, March 31, 2013    Clinical Article

45 Evaluation of serum biomarkers associated with radiographic progression in methotrexate-naive rheumatoid arthritis patients treated with methotrexate or golimumab The Journal of Rheumatology, March 31, 2013    Clinical Article

46 HLA-G may predict the disease course in patients with early rheumatoid arthritis Human Immunology, March 31, 2013    Review Article    Clinical Article

47 Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial Annals of Rheumatic Diseases, March 31, 2013    Clinical Article

48 Adalimumab: long-term safety in 23458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohns disease Annals of Rheumatic Diseases, March 17, 2013    Clinical Article

49 Changes in lipoproteins associated with treatment with methotrexate or combination therapy in early rheumatoid arthritis: Results from the TEAR trial Arthritis & Rheumatism, March 17, 2013    Clinical Article

50 Occurrence and relative risk of stroke in incident and prevalent contemporary rheumatoid arthritis Annals of Rheumatic Diseases, March 17, 2013    Clinical Article

51 Subcutaneous abatacept for the treatment of rheumatoid arthritis Rheumatology, March 17, 2013    Clinical Article

52 Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial Annals of Rheumatic Diseases, March 17, 2013    Clinical Article

53 Periarticular Bone Gain at Proximal Interphalangeal Joints and Changes in Bone Turnover Markers in Response to Tumor Necrosis Factor Inhibitors in Rheumatoid and Psoriatic Arthritis The Journal of Rheumatology, March 17, 2013    Clinical Article

54 Exposure to ultraviolet-B and risk of developing rheumatoid arthritis among women in the Nurses Health Study Annals of Rheumatic Diseases, March 17, 2013    Clinical Article

55 Parental history of lupus and rheumatoid arthritis and risk in offspring in a nationwide cohort study: does sex matter Annals of Rheumatic Diseases, March 17, 2013    Clinical Article

56 Risk of rheumatoid arthritis development in patients with unclassified arthritis according to the 2010 ACR/EULAR criteria for rheumatoid arthritis Rheumatology, March 17, 2013    Clinical Article

Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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