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Rheumatology News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (24) Full Text Articles (287) Focus on Osteoporosis
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Disease-modifying drugs for knee osteoarthritis: can they be cost-effective Osteoarthritis and Cartilage , May 21, 2013    Clinical Article

2 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, May 21, 2013    Clinical Article

3 Comparison of Intra-Articular Hyaluronic Acid Injections with Transcutaneous Electric Nerve Stimulation for the Management of Knee Osteoarthritis: A Randomized Controlled Trial Archives of Physical Medicine and Rehabilitation, May 21, 2013    Clinical Article

4 Comparing the effects of individualized, standard, sham and no acupuncture in the treatment of knee osteoarthritis: a multicenter randomized controlled trial Full Text Trials, May 21, 2013    Clinical Article

5 Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

6 MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative Arthritis & Rheumatism, May 21, 2013    Clinical Article

7 The relationship between fatigue and subsequent physical activity among older adults with symptomatic osteoarthritis Arthritis Care & Research , May 21, 2013    Clinical Article

8 Association of the sense of coherence with physical and psychosocial health in the rehabilitation of osteoarthritis of the hip and knee: a prospective cohort study Full Text BMC Musculoskeletal Disorders, May 21, 2013    Clinical Article

9 Biomechanical deviations during level walking associated with knee osteoarthritis: A systematic review and meta-analysis Arthritis Care & Research , May 21, 2013    Evidence Based Medicine    Clinical Article

10 Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative Annals of Rheumatic Diseases, May 7, 2013    Clinical Article

11 EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis Annals of Rheumatic Diseases, May 7, 2013    Clinical Article

12 A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee Pain, May 7, 2013    Clinical Article

13 Association of frequent knee bending activity with focal knee lesions detected with 3T MRI - data from the Osteoarthritis Initiative Arthritis Care & Research , May 7, 2013    Clinical Article

14 Subchondral bone trabecular integrity predicts and changes concurrently with radiographic and MRI determined knee osteoarthritis progression Arthritis & Rheumatism, May 7, 2013    Clinical Article

15 Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: results from a randomized controlled pilot study Full Text BMC Musculoskeletal Disorders, May 7, 2013    Clinical Article

16 Kynurenic Acid in Synovial Fluid and Serum of Patients with Rheumatoid Arthritis, Spondyloarthropathy, and Osteoarthritis The Journal of Rheumatology, May 7, 2013    Clinical Article

17 Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study Full Text BMC Musculoskeletal Disorders, May 7, 2013    Clinical Article

18 Quantitative MRI measures of cartilage predict knee replacement: a case-control study from the Osteoarthritis Initiative Annals of Rheumatic Diseases, May 7, 2013    Clinical Article

19 Relationship of bone mineral density to progression of knee osteoarthritis Arthritis & Rheumatism, April 23, 2013    Clinical Article

20 Improvement in knee loading after use of specialized footwear for knee osteoarthritis: Results of a 6-month pilot investigation Arthritis & Rheumatism, April 23, 2013    Clinical Article

21 Tanezumab reduces osteoarthritic hip pain: Results of a randomized, double-blind, placebo-controlled phase 3 trial Arthritis & Rheumatism, April 23, 2013    Clinical Article

22 Responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) scale in a trial of duloxetine for treatment of osteoarthritis knee pain Osteoarthritis and Cartilage , April 23, 2013    Clinical Article

23 The Efficacy of Diacerein in Hand Osteoarthritis: A Double-Blind, Randomized, Placebo-Controlled Study Clinical Therapeutics, April 23, 2013    Clinical Article

24 Diagnostic and prognostic value of bone biomarkers in progressive knee osteoarthritis: a 6-year follow-up study in middle-aged subjects Osteoarthritis and Cartilage , April 23, 2013    Clinical Article

25 Diclofenac in the treatment of osteoarthritis International Journal of Clinical Rheumatology, April 23, 2013    Clinical Article

26 A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthritis Rheumatology, April 23, 2013    Clinical Article

27 A novel disease-modifying osteoarthritis drug candidate targeting Runx1 Annals of Rheumatic Diseases, April 23, 2013    Clinical Article

28 Physical activity, alignment and knee osteoarthritis: data from MOST and the OAI Osteoarthritis and Cartilage , April 23, 2013    Clinical Article

29 The value of cartilage biomarkers in progressive knee osteoarthritis: cross-sectional and 6-year follow-up study in middle-aged subjects Rheumatology International, April 23, 2013    Clinical Article

30 The effect of osteoarthritis of the knee on the biomechanics of other joints in the lower limbs The Bone & Joint Journal, March 28, 2013    Clinical Article

31 Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study Journal of General Internal Medicine, March 28, 2013    Clinical Article

32 Computed tomography for the detection of thumb base osteoarthritis: comparison with digital radiography Skeletal Radiology, March 28, 2013    Clinical Article

33 Greater Number of Narcotic Analgesic Prescriptions for Osteoarthritis Is Associated with Falls and Fractures in Elderly Adults Journal of the American Geriatrics Society, March 28, 2013    Clinical Article

34 Elaboration and validation of a questionnaire assessing patient expectations about management of knee osteoarthritis by their physicians: the Knee Osteoarthritis Expectations Questionnaire Annals of Rheumatic Diseases, March 28, 2013    Clinical Article

35 Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation Arthritis Research & Therapy, March 28, 2013    Clinical Article

36 Meniscus body position, size and shape in persons with and without radiographic knee osteoarthritis: Quantitative analyses of knee MRIs from the Osteoarthritis Initiative Arthritis & Rheumatism, March 28, 2013    Clinical Article

37 The association between reduced knee joint proprioception and medial meniscal abnormalities using MRI in knee osteoarthritis: results from the Amsterdam osteoarthritis cohort Osteoarthritis and Cartilage , March 28, 2013    Clinical Article

38 Bone mineralization is elevated and less heterogeneous in adults with type 2 diabetes and osteoarthritis compared to controls with osteoarthritis alone Bone, March 28, 2013    Review Article

39 Clustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee Annals of Rheumatic Diseases, March 14, 2013    Clinical Article

40 Transthyretin as a potential serological marker for the diagnosis of patients with early rheumatoid arthritis Clinical and Experimental Rheumatology Online, March 14, 2013    Clinical Article

41 Histopathological correlation supports the use of x-rays in the diagnosis of hand osteoarthritis Annals of Rheumatic Diseases, March 14, 2013    Clinical Article

Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013

2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013    Evidence Based Medicine    Review Article

3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013

4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013

5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013    Free full text

6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013

7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013

8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013    Review Article    Clinical Guideline

9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013

10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013

11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013

12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013    Free full text

13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013    Evidence Based Medicine

14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013    Free full text

15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013

16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013

17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013    Evidence Based Medicine

18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013

19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013

20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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