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Rheumatology - Rheumatoid Arthritis News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (3) Full Text Articles (48) Focus on Osteoporosis101 Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis Annals of Rheumatic Diseases, April 22, 2013 Evidence Based Medicine Review Article Clinical Article
102 A phase 2 dose-ranging study of subcutaneous tabalumab for the treatment of patients with active rheumatoid arthritis and an inadequate response to methotrexate Annals of Rheumatic Diseases, April 22, 2013 Clinical Article
103 Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA Annals of Rheumatic Diseases, April 22, 2013 Clinical Article
104 A non-inferiority trial of an attenuated combination strategy (COBRA-light) compared to the original COBRA strategy: clinical results after 26 weeks Annals of Rheumatic Diseases, April 22, 2013 Clinical Article
105 The role of miR-155 in regulatory T cells and rheumatoid arthritis Clinical Immunology, April 22, 2013 Review Article
106 A simple model that suggests possible cost savings when modified-release prednisone 5 mg/day is added to current treatment in patients with active rheumatoid arthritis Rheumatology, April 19, 2013 Clinical Article
107 Periodontal Disease and Rheumatoid Arthritis: A Systematic Review Journal of Dental Research , April 19, 2013 Review Article Clinical Article
108 The Biological and Clinical Activity of Anti-Malarial Drugs In Autoimmune Disorders Current Rheumatology Reviews, April 19, 2013 Review Article Clinical Article
109 Clinical Response Within 12 Weeks as a Predictor of Future Low Disease Activity in Patients with Early RA: Results from the TEAR Trial The Journal of Rheumatology, April 18, 2013 Clinical Article
110 Kynurenic Acid in Synovial Fluid and Serum of Patients with Rheumatoid Arthritis, Spondyloarthropathy, and Osteoarthritis The Journal of Rheumatology, April 18, 2013 Clinical Article
111 Association of Polymorphisms Modulating Low-density Lipoprotein Cholesterol with Susceptibility, Severity, and Progression of Rheumatoid Arthritis The Journal of Rheumatology, April 18, 2013 Clinical Article
112 Novel risk factors for cardiovascular disease in rheumatoid arthritis Immunologic Research, April 18, 2013 Evidence Based Medicine Review Article Clinical Article
113 Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: A validation study using the medical records of rheumatologists Arthritis Care & Research , April 18, 2013 Clinical Article
114 Cross-cultural adaptation and validation of the Thai version of the Rheumatoid Arthritis Disease Activity Index (RADAI) Rheumatology International, April 18, 2013 Clinical Article
115 Level of knowledge and sources of information about the rheumatoid arthritis in Estonian patients Rheumatology International, April 18, 2013 Review Article
116 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013 Clinical Article
117 Prognostic Factors and Radiographic Outcomes of Nontuberculous Mycobacterial Lung Disease in Rheumatoid Arthritis The Journal of Rheumatology, April 17, 2013 Clinical Article
118 TNF inhibitors induce discoid fibrosis in the sublining layers of the synovium with degeneration of synoviocytes in rheumatoid arthritis Rheumatology International, April 17, 2013 Review Article
119 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013 Clinical Article
120 The ability of synovitis to predict structural damage in rheumatoid arthritis: a comparative study between clinical examination and ultrasound Annals of Rheumatic Diseases, April 16, 2013 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 The new European League Against Rheumatism/American College of Rheumatology diagnostic criteria for rheumatoid arthritis: how are they performing Current Opinion in Rheumatology, April 4, 2013
2 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
3 New methods for determining comparative effectiveness in rheumatoid arthritis Current Opinion in Rheumatology, April 3, 2013
4 Rheumatoid arthritis in the elderly: recent advances in understanding the pathogenesis, risk factors, comorbidities and risk-benefit of treatments Aging Health, April 11, 2013 Review Article
5 Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis Annals of Rheumatic Diseases, April 22, 2013 Evidence Based Medicine Review Article
6 Clinical Response Within 12 Weeks as a Predictor of Future Low Disease Activity in Patients with Early RA: Results from the TEAR Trial The Journal of Rheumatology, April 18, 2013
7 Long-term therapeutic effects and safety of tacrolimus added to methotrexate in patients with rheumatoid arthritis Rheumatology International, April 5, 2013
8 Efficacy and Safety of Belimumab in Patients with Rheumatoid Arthritis: A Phase II, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study The Journal of Rheumatology, April 2, 2013
9 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
10 Treatment strategies for early rheumatoid arthritis Current Opinion in Rheumatology, April 1, 2013
11 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
12 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Annals of Rheumatic Diseases, April 9, 2013
13 Does Acetaminophen Activate Endogenous Pain Inhibition in Chronic Fatigue Syndrome/Fibromyalgia and Rheumatoid Arthritis? A Double-Blind Randomized Controlled Cross-over Trial Pain Physician, March 25, 2013 Free full text
14 Remission in patients with active rheumatoid arthritis by tocilizumab treatment in routine clinical practice: results from 3 years of prospectively registered data Modern Rheumatology, April 9, 2013
15 Adalimumab: 8 years of experience in rheumatoid arthritis International Journal of Clinical Rheumatology, April 2, 2013
16 A simple model that suggests possible cost savings when modified-release prednisone 5 mg/day is added to current treatment in patients with active rheumatoid arthritis Rheumatology, April 19, 2013
17 What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review Annals of Rheumatic Diseases, April 23, 2013 Evidence Based Medicine Review Article
18 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
19 Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial Annals of Rheumatic Diseases, April 8, 2013
20 Impact of etanercept on work and activity impairment in employed moderate to severe rheumatoid arthritis patients in the United States Arthritis Care & Research , April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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