What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
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361 Interaction between oxidative stress and smoking is associated with an increased risk of rheumatoid arthritis: a case-control study Rheumatology, February 21, 2013 Clinical Article
362 Association between -871C>T promoter polymorphism in the B-cell activating factor gene and the response to rituximab in rheumatoid arthritis patients Rheumatology, February 21, 2013 Review Article
363 IL-17-mediated Bcl-2 expression regulates survival of fibroblast like synoviocytes in rheumatoid arthritis through STAT3 activation Arthritis Research & Therapy, February 21, 2013 Review Article
364 Efficacy and safety of leflunomide in DMARD-naive patients with early rheumatoid arthritis: comparison of a loading and a fixed-dose regimen Rheumatology, February 20, 2013 Clinical Article
365 Characteristics of Sjogrens syndrome in rheumatoid arthritis Rheumatology, February 20, 2013 Clinical Guideline
366 Changes in bone mineral density during long-term treatment with adalimumab in patients with rheumatoid arthritis: a cohort study Rheumatology, February 19, 2013 Clinical Article
367 Quantitative and Semiquantitative Bone Erosion Assessment on High-resolution Peripheral Quantitative Computed Tomography in Rheumatoid Arthritis The Journal of Rheumatology, February 19, 2013 Review Article
368 Macrophage migration inhibitory factor (MIF): Genetic evidence for participation in early onset and early stage rheumatoid arthritis Cytokine, February 19, 2013 Review Article
369 Influence of interleukin-4 gene polymorphisms and interleukin-4 serum level on susceptibility and severity of rheumatoid arthritis in Egyptian population Cytokine, February 19, 2013 Review Article
370 Rheumatoid and pyrophosphate arthritis synovial fibroblasts induce osteoclastogenesis independently of RANKL, TNF and IL-6 Journal of Autoimmunity , February 19, 2013 Review Article
371 Clinical outcome in patients with rheumatoid arthritis switched to tocilizumab after etanercept or infliximab failure Clinical Rheumatology, February 18, 2013 Clinical Article
372 Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial Rheumatology, February 18, 2013 Clinical Article
373 Efficacy of the switch to modified-release prednisone in rheumatoid arthritis patients treated with standard glucocorticoids Clinical and Experimental Rheumatology Online, February 18, 2013 Clinical Article
374 Postpublication validation of the 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: where do we stand Current Opinion in Rheumatology, February 18, 2013 Clinical Guideline
375 The temporal relationship between depression and rheumatoid arthritis disease activity, treatment persistence and response: a systematic review Rheumatology, February 18, 2013 Evidence Based Medicine Clinical Article
376 The Role of the Microbiome in Rheumatic Diseases Current Rheumatology Reports, February 18, 2013 Clinical Guideline
377 Positive synovial vascularity in patients with low disease activity indicates smouldering inflammation leading to joint damage in rheumatoid arthritis: time-integrated joint inflammation estimated by synovial vascularity in each finger joint Rheumatology, February 18, 2013 Review Article
378 Similar clinical outcomes in rheumatoid arthritis with more versus less expensive treatment strategies. Observational data from two rheumatology clinics Clinical and Experimental Rheumatology Online, February 18, 2013 Clinical Guideline
379 Gender Differences in Latin-American Patients With Rheumatoid Arthritis Gender Medicine, February 18, 2013 Evidence Based Medicine
380 Lessons to be learned from periodontitis Current Opinion in Rheumatology, February 18, 2013 Review Article
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryIn a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryIn a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryIndexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
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