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Rheumatology - Clinical Pharmacology News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (9) Full Text Articles (47) Focus on Osteoarthritis
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Steroid injection for inferior heel pain: a randomised controlled trial Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

2 Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

3 Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study) Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

4 Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

5 A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

6 Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

7 Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

8 Efficacy of rituximab in systemic manifestations of primary Sjogrens syndrome: results in 78 patients of the AutoImmune and Rituximab registry Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

9 Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry Annals of Rheumatic Diseases, May 22, 2013    Clinical Article

Prior Articles

10 Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1) Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

11 A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

12 Induction therapy with adalimumab plus methotrexate for 24 weeks followed by methotrexate monotherapy up to week 48 versus methotrexate therapy alone for DMARD-naive patients with early rheumatoid arthritis: HIT HARD, an investigator-initiated study Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

13 Juvenile idiopathic arthritis: an update on current pharmacotherapy and future perspectives Expert Opinion on Pharmacotherapy, May 21, 2013    Clinical Article

14 Behcet Disease-associated Uveitis Successfully Treated with Golimumab Ocular Immunology and Inflammation, May 21, 2013    Clinical Article

15 Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis Clinical and Experimental Rheumatology Online, May 20, 2013    Evidence Based Medicine    Review Article    Clinical Article

16 Validation of methotrexate-first strategy in early poor prognosis rheumatoid arthritis: Results from a randomized, double-blind, 2-year trial Arthritis & Rheumatism, May 20, 2013    Clinical Article

17 Diabetes and gout: efficacy and safety of febuxostat and allopurinol Diabetes, Obesity and Metabolism, May 20, 2013    Clinical Article

18 Treatment of ankylosing spondylitis with TNF blockers: a meta-analysis Rheumatology International, May 20, 2013    Evidence Based Medicine    Review Article    Clinical Article

19 Tocilizumab Treatment for Nephrotic Syndrome Due to Amyloidosis in Behcets Disease Renal Failure, May 20, 2013

20 Bisphosphonate use and subsequent hip fracture in South Korea Osteoporosis International, May 20, 2013    Clinical Article

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Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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