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Rheumatology - Osteoarthritis News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (3) Full Text Articles (25) Focus on Osteoarthritis381 Is Pain and Dissatisfaction After TKA Related to Early-grade Preoperative Osteoarthritis Clinical Orthopedics and Related Research, September 11, 2012
382 A randomized, double-blind, placebo-controlled trial of low dose oral prednisolone for treating painful hand osteoarthritis Rheumatology, September 10, 2012 Clinical Article
383 Osteoporosis and shoulder osteoarthritis: incidence, risk factors, and surgical implications Journal of Shoulder and Elbow Surgery, September 10, 2012
384 Living experiences of middle-aged adults with early knee osteoarthritis in prediagnostic phase Disability & Rehabilitation, September 10, 2012
385 Intra-articular lentivirus-mediated insertion of the fat-1 gene ameliorates osteoarthritis Medical Hypotheses, September 7, 2012
386 Diagnosis of osteoarthritis and prognosis of tibial cartilage loss by quantification of tibia trabecular bone from MRI Magnetic Resonance in Medicine, September 7, 2012 Clinical Article
387 MRI-guided focused ultrasound (MRgFUS) to treat facet joint osteoarthritis low back pain--case series of an innovative new technique European Radiology, September 6, 2012 Clinical Article
388 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study The Lancet, September 6, 2012
389 Treatment Satisfaction after Switching to Another Therapy in Spanish Orthopaedic Clinic Outpatients with Knee or Hip Osteoarthritis Previously Refractory to Paracetamol Clinical Drug Investigation, September 6, 2012 Clinical Article
390 A physiotherapist-delivered, combined exercise and pain coping skills training intervention for individuals with knee osteoarthritis: A pilot study The Knee, August 31, 2012 Clinical Article
391 Stress-induced cartilage degradation does not depend on NLRP3 inflammasome in osteoarthritis Arthritis & Rheumatism, August 31, 2012
392 Perception and presentation of function in patients with unilateral versus bilateral knee osteoarthritis Arthritis Care & Research , August 31, 2012
393 Diminished cartilage lubricating ability of human osteoarthritic synovial fluid deficient in proteoglycan 4: Restoration through proteoglycan 4 supplementation Arthritis & Rheumatism, August 31, 2012
394 Difficulties with assessing the benefit of glucosamine sulphate as a treatment for osteoarthritis International Journal of Evidence-Based Healthcare, August 30, 2012 Clinical Article
395 Pharmacist initiated intervention trial in osteoarthritis (PhIT-OA): A multidisciplinary intervention for knee osteoarthritis Arthritis Care & Research , August 30, 2012
396 Effects of weekly and fortnightly therapeutic exercise on physical function and health-related quality of life in individuals with hip osteoarthritis Journal of Orthopaedic Science, August 30, 2012
397 The natural history of bone bruise and bone remodelling in the traumatised hip: A prospective 2-year follow-up study of bone bruise changes and DEXA measurements in 13 patients with conservatively treated traumatic hip dislocations and/or fractures Injury, August 30, 2012
398 Imputing At-Work Productivity Loss Using Results of a Randomized Controlled Trial Comparing Tapentadol Extended Release and Oxycodone Controlled Release for Osteoarthritis Pain Journal of Occupational and Environmental Medicine, August 29, 2012 Clinical Article
399 Total Hip Arthroplasty, Hip Osteoarthritis, Total Knee Arthroplasty, and Knee Osteoarthritis in Patients With Developmental Dysplasia of the Hip and Their Family Members: A Kinship Analysis Report Journal of Pediatric Orthopaedics , August 29, 2012
400 Ankle Distraction Arthroplasty Combined with Joint Resurfacing for Management of an Osteochondral Defect of the Talus and Concomitant Osteoarthritis: A Case Report The Journal of Foot & Ankle Surgery, August 29, 2012
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 New horizons in osteoarthritis Age and Aging, April 11, 2013 Review Article
3 Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study Journal of General Internal Medicine, March 25, 2013
4 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 5, 2013 Review Article Clinical Guideline
5 A novel disease-modifying osteoarthritis drug candidate targeting Runx1 Annals of Rheumatic Diseases, April 8, 2013
6 Diagnostic and prognostic value of bone biomarkers in progressive knee osteoarthritis: a 6-year follow-up study in middle-aged subjects Osteoarthritis and Cartilage , April 16, 2013
7 Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study Annals of Rheumatic Diseases, April 10, 2013
8 The Efficacy of Diacerein in Hand Osteoarthritis: A Double-Blind, Randomized, Placebo-Controlled Study Clinical Therapeutics, April 17, 2013
9 Diclofenac in the treatment of osteoarthritis International Journal of Clinical Rheumatology, April 2, 2013
10 Relationship of bone mineral density to progression of knee osteoarthritis Arthritis & Rheumatism, April 4, 2013
11 A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthritis Rheumatology, April 1, 2013
12 Biologic agents in osteoarthritis: hopes and disappointments Nature Reviews Rheumatology , April 5, 2013
13 Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation Arthritis Research & Therapy, March 21, 2013
14 The value of cartilage biomarkers in progressive knee osteoarthritis: cross-sectional and 6-year follow-up study in middle-aged subjects Rheumatology International, April 3, 2013
15 Kynurenic Acid in Synovial Fluid and Serum of Patients with Rheumatoid Arthritis, Spondyloarthropathy, and Osteoarthritis The Journal of Rheumatology, April 18, 2013
16 Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative Annals of Rheumatic Diseases, April 23, 2013
17 Improvement in knee loading after use of specialized footwear for knee osteoarthritis: Results of a 6-month pilot investigation Arthritis & Rheumatism, April 11, 2013
18 The pathogenesis of osteoarthritis involves bone, cartilage and synovial inflammation: may estrogen be a magic bullet? Menopause International, April 11, 2013
19 Physical activity, alignment and knee osteoarthritis: data from MOST and the OAI Osteoarthritis and Cartilage , April 19, 2013
20 EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis Annals of Rheumatic Diseases, April 24, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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