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Rheumatology - Bone Metabolism News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (8) Full Text Articles (73) Focus on Gout
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 A review on strontium ranelate long-term antifracture efficacy in the treatment of postmenopausal osteoporosis Therapeutic Advances in Musculoskeletal Disease, June 20, 2013    Clinical Article

2 Alterations of bone geometry, density, microarchitecture, and biomechanical properties in systemic lupus erythematosus on long-term glucocorticoid: a case-control study using HR-pQCT Osteoporosis International, June 20, 2013    Clinical Article

3 Hand bone loss in patients with psoriatic arthritis: posthoc analysis of IMPACT II data comparing infliximab and placebo The Journal of Rheumatology, June 20, 2013    Clinical Article

4 Bisphosphonates as a supplement to exercise to protect bone during long-duration spaceflight Osteoporosis International, June 20, 2013    Clinical Article

5 Lumbar disc degeneration in osteoporotic men: prevalence and assessment of the relation with presence of vertebral fracture The Journal of Rheumatology, June 20, 2013    Review Article

6 Wif-1-deficiency uncouples cartilage and bone destruction in TNF-mediated experimental arthritis Arthritis & Rheumatism, June 20, 2013    Review Article

7 Bone mineral density evolution after successful parathyroidectomy in patients with normocalcemic primary hyperparathyroidism Journal of Clinical Endocrinology and Metabolism, June 20, 2013    Clinical Article

8 On genome-wide association studies and their meta-analyses: lessons learned from osteoporosis studies Journal of Clinical Endocrinology and Metabolism, June 20, 2013    Evidence Based Medicine

Prior Articles

9 Cryofibrinogen levels are increased in non-traumatic osteonecrosis: a new pathogenic clue to osteonecrosis Rheumatology, June 19, 2013    Review Article

10 Beyond glycemic control in diabetes mellitus: effects of incretin-based therapies on bone metabolism Frontiers in Endocrinology, June 19, 2013    Review Article

11 Bone quality in diabetes Frontiers in Endocrinology, June 19, 2013    Review Article

12 New genes in bone development: what’s new in osteogenesis imperfecta Journal of Clinical Endocrinology and Metabolism, June 19, 2013    Review Article

13 Non-sex cord-stromal ovarian tumors frequently produce and secrete estrogen in postmenopausal women: impact on bone metabolism and abnormal endometrial histology Journal of Clinical Endocrinology and Metabolism, June 19, 2013    Review Article

14 Dietary B vitamin intake and risk of hip fracture: The Singapore Chinese Health Study Osteoporosis International, June 18, 2013    Clinical Article
Exclusive Author Commentary

15 Effects of exercise on fracture reduction in older adults Osteoporosis International, June 18, 2013    Evidence Based Medicine    Review Article    Clinical Article

16 Predictors of the rate of BMD loss in older men: findings from the CHAMP study Osteoporosis International, June 18, 2013    Clinical Article

17 Circulating activin-A is elevated in postmenopausal women with low bone mass: the three-month effect of zoledronic acid treatment Osteoporosis International, June 18, 2013    Clinical Article

18 Bone density and neuromuscular function in older competitive athletes depend on running distance Osteoporosis International, June 18, 2013    Review Article

19 A meta-analysis of the association of fracture risk and body mass index in women Journal of Bone and Mineral Research, June 18, 2013    Evidence Based Medicine

20 Association between metabolome and low bone mineral density in Taiwanese women determined by 1H NMR Spectroscopy Journal of Bone and Mineral Research, June 18, 2013    Clinical Article

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Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013

2 Bisphosphonate-related osteonecrosis of the jaw in non-malignant bone disease Rheumatology International, May 10, 2013

3 Association of clinical features of bone and joint lesions between children and parents with Kashin-Beck disease in Northwest China Clinical Rheumatology, May 2, 2013

4 MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative Arthritis & Rheumatism, May 6, 2013

5 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013

6 Clinical Aspects of Hypophosphatasia: An Update Clinical Reviews in Bone and Mineral Metabolism , May 21, 2013    Review Article

7 Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling Evidence-based Complementary and Alternative Medicine , May 17, 2013    Free full text

8 Periarticular and generalised bone loss in patients with early rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial Annals of Rheumatic Diseases, May 23, 2013

9 Osteoporosis treatment European Journal of Internal Medicine , April 25, 2013

10 Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis Annals of Rheumatic Diseases, May 22, 2013    Review Article

11 Ankle fractures have features of an osteoporotic fracture Osteoporosis International, May 20, 2013    Review Article

12 Does the cement stiffness affect fatigue fracture strength of vertebrae after cement augmentation in osteoporotic patients? European Spine Journal, May 16, 2013    Evidence Based Medicine

13 A randomized trial comparing monthly ibandronate and weekly alendronate for osteoporosis in patients with primary biliary cirrhosis Hepatology, May 22, 2013

14 Trabecular homogeneity index derived from plain radiograph to evaluate bone quality Journal of Bone and Mineral Research, May 16, 2013    Review Article

15 The role of vitamin D supplementation in patients with rheumatic diseases Nature Reviews Rheumatology , May 15, 2013    Clinical Guideline

16 Dual-energy X-ray absorptiometry versus quantitative ultrasonography in diagnosing osteoporosis in patients with refractory epilepsy and chronic antiepileptic drug use Therapeutic Advances in Musculoskeletal Disease, May 3, 2013

17 Deletion of the receptor tyrosine kinase Tyro3 inhibits synovial hyperplasia and bone damage in arthritis Annals of Rheumatic Diseases, May 7, 2013    Review Article

18 Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study Journal of Clinical Endocrinology and Metabolism, April 5, 2013

19 Relationship of bone mineral density to progression of knee osteoarthritis Arthritis & Rheumatism, April 4, 2013

20 Osteitis and synovitis, but not bone erosion, is associated with proteoglycan loss and microstructure damage in the cartilage of patients with rheumatoid arthritis Annals of Rheumatic Diseases, May 7, 2013    Review Article

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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