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Peds Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest Full Text Articles (13) Focus on Osteoporosis381 Thrombotic microangiopathy due to multiple autoantibodies related to antiphospholipid syndrome Pediatric Nephrology, January 11, 2012
382 Juvenile lupus erythematosus: Fourteen years of experience Turkish Journal of Rheumatology, January 10, 2012
383 Age-related differences in the clinical characteristics of systemic lupus erythematosus in children Rheumatology International, January 10, 2012
384 Evaluation of the current disease severity scores in pediatric FMF: Is it necessary to develop a new one? Rheumatology, January 6, 2012
385 Relapsing polychondritis in childhood: three case reports, comparison with adulthood disease and literature review Rheumatology International, January 6, 2012
386 Markers of systemic inflammation in children with hyperuricemia Acta Pediatrica, January 6, 2012
387 Genetic association study of NF-&kappaB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy Rheumatology, January 4, 2012
388 Safety and efficacy of US-guided CS injection into temporomandibular joints in children with active JIA Rheumatology, January 4, 2012
389 Attitudes of rheumatology practitioners toward transition and transfer from pediatric to adult healthcare Rheumatology International, December 30, 2011
390 Evaluation of the current disease severity scores in pediatric FMF: Is it necessary to develop a new one? Rheumatology, December 23, 2011
391 Scleritis: A paradoxical effect of etanercept? Etanercept-associated inflammatory eye disease The Journal of Rheumatology, December 23, 2011
392 Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study Annals of Rheumatic Diseases, December 23, 2011
393 Health-related quality of life and psychosocial developmental trajectory in young female beneficiaries with JIA Rheumatology, December 23, 2011
394 Measurement of autoantibodies in pediatric-onset systemic lupus erythematosus and their relationship with disease-associated manifestations Seminars in Arthritis and Rheumatism, December 21, 2011
395 Prevalence of annexin A5 resistance in children and adolescents with rheumatic diseases The Journal of Rheumatology, December 19, 2011
396 Simultaneous Juvenile Idiopathic Arthritis and Diabetes Mellitus Type 1 -- A Finnish Nationwide Study The Journal of Rheumatology, December 16, 2011 Clinical Article
397 Fatigue in survivors of childhood acute lymphoblastic and myeloid leukemia in Japan Pediatrics International, December 15, 2011
398 Damage index in childhood-onset systemic lupus erythematosus in Egypt Pediatric Rheumatology, December 13, 2011
399 Differences in clinical manifestations between childhood-onset lupus and adult-onset lupus: a meta-analysis Lupus, December 9, 2011 Evidence Based Medicine
400 Factors associated with treatment response to etanercept in juvenile idiopathic arthritis Full Text JAMA, December 8, 2011 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Superior efficacy of Adalimumab in treating childhood refractory chronic uveitis when used as first biologic modifier drug: Adalimumab as starting anti-TNF-alpha therapy in childhood chronic uveitis Pediatric Rheumatology, April 16, 2013
2 Hypermobility is a risk factor for musculoskeletal pain in adolescence: Findings from a prospective cohort study Arthritis & Rheumatism, April 2, 2013
3 Role of methotrexate in juvenile idiopathic arthritis: where we have been and where we are going International Journal of Clinical Rheumatology, March 25, 2013 Review Article
4 Race, Ethnicity, and Disease Outcomes in Juvenile Idiopathic Arthritis: A Cross-sectional Analysis of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry The Journal of Rheumatology, April 18, 2013
5 Achievement of clinical remission in patients with juvenile idiopathic arthritis under a 2-10-year Etanercept exposure Clinical Rheumatology, April 22, 2013
6 Chronic Non-bacterial Osteomyelitis in Childhood a Comprehensive Review Current Rheumatology Reviews, April 23, 2013 Review Article
7 The Impact of Evidence-Based Clinical Practice Guidelines Applied by a Multidisciplinary Team for the Care of Children with Osteomyelitis The Journal of Bone & Joint Surgery, April 19, 2013 Clinical Guideline
8 Chronic recurrent multifocal osteomyelitis (CRMO): a longitudinal case series review Pediatric Radiology, February 22, 2013 Review Article
9 Antiphospholipid antibodies in children with systemic lupus erythematosus: a long-term clinical and laboratory follow-up status study from northwest India Rheumatology International, April 8, 2013
10 The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis Annals of Rheumatic Diseases, April 15, 2013 Review Article
11 Juvenile Psoriatic Arthritis (JPsA): juvenile arthritis with psoriasis Pediatric Rheumatology, March 19, 2013 Review Article
12 Incidence and Prevalence of Juvenile Idiopathic Arthritis Among Children in a Managed Care Population, 1996-2009 The Journal of Rheumatology, April 17, 2013
13 Understanding why cognitivebehavioral therapy is an effective treatment for adolescents with juvenile fibromyalgia International Journal of Clinical Rheumatology, April 5, 2013
14 Out-of-clinic patient communication in paediatric rheumatology: the extent and nature of demand Pediatric Rheumatology, March 28, 2013 Review Article
15 Cardiovascular risk in juvenile idiopathic arthritis Rheumatology, March 18, 2013
16 Long-Term Bone Health in Glucocorticoid-Treated Children with Rheumatic Diseases Current Rheumatology Reports, February 4, 2013
17 Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis Pediatric Rheumatology, April 3, 2013 Review Article
18 Updates on the risk markers and outcomes of severe juvenile idiopathic arthritis-associated uveitis International Journal of Clinical Rheumatology, April 2, 2013
19 Familial Mediterranean fever in heterozygotes: Are we able to accurately diagnose the disease in very young children Arthritis & Rheumatism, March 19, 2013 Clinical Guideline
20 MEFV gene mutations in Turkish children with juvenile idiopathic arthritis European Journal of Pediatrics, April 26, 2013 Review Article
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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