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Rheumatology - Autoimmune/Heritable News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (2) Full Text Articles (22) Focus on Osteoporosis
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

81 Development and initial validation of the Indian Takayasu Clinical Activity Score (ITAS2010) Rheumatology, April 25, 2013    Review Article

82 Relapsing Polychondritis Rheumatic Disease Clinics of North America, April 25, 2013    Review Article

83 Evaluation of an automated chemiluminescent immunoassay kit for antinuclear antibodies in autoimmune diseases Immunologic Research, April 25, 2013    Clinical Article

84 Epilepsy Associated with Systemic Autoimmune Disorders Full Text Epilepsy Currents, April 25, 2013    Clinical Article

85 Localized Cutaneous Fibrosing Disorders Rheumatic Disease Clinics of North America, April 25, 2013    Review Article

86 Autoantibodies in Polymyositis and Dermatomyositis Current Rheumatology Reports, April 24, 2013    Review Article

87 Rituximab in refractory idiopathic inflammatory myopathies and antisynthetase syndrome: personal experience and review of the literature Immunologic Research, April 24, 2013    Review Article    Clinical Article

88 Long-term outcomes of 118 patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) enrolled in two prospective trials Journal of Autoimmunity , April 24, 2013    Clinical Article

89 B-cell depletion therapy and pregnancy outcome in severe, refractory systemic autoimmune diseases Journal of Autoimmunity , April 24, 2013    Clinical Article

90 Refractory pemphigus foliaceus and Behçets disease successfully treated with tocilizumab Immunologic Research, April 24, 2013

91 The prevalence of fibromyalgia in patients with Behcets disease and its relation with disease activity Rheumatology International, April 23, 2013    Clinical Article

92 Erdheim-Chester Disease Rheumatic Disease Clinics of North America, April 23, 2013    Review Article

93 Association of TNFSF4 polymorphisms with susceptibility to primary Sjogren`s syndrome and primary biliary cirrhosis in a Chinese Han population Clinical and Experimental Rheumatology Online, April 23, 2013    Review Article

94 TDP-43 frontotemporal lobar degeneration and autoimmune disease Journal of Neurology, Neurosurgery & Psychiatry, April 23, 2013    Review Article

95 A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies Rheumatology, April 23, 2013    Review Article

96 Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis Arthritis Research & Therapy, April 22, 2013    Clinical Article

97 Immunoglobulin light chain amyloidosis: 2013 update on diagnosis, prognosis, and treatment American Journal of Hematology, April 22, 2013    Clinical Article

98 ANA (+) ANCA (+) systemic vasculitis associated with the use of minocycline: case-based review Clinical Rheumatology, April 22, 2013    Review Article

99 Variable presentation of primary immune deficiency: Two cases with CD3 gamma deficiency presenting with only autoimmunity Pediatric Allergy and Immunology, April 22, 2013

100 Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis Annals of Rheumatic Diseases, April 22, 2013    Review Article

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Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013

2 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013

3 Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis Arthritis Research & Therapy, April 22, 2013

4 Antiphospholipid antibodies in children with systemic lupus erythematosus: a long-term clinical and laboratory follow-up status study from northwest India Rheumatology International, April 8, 2013

5 Skin and Mucosa Care in Systemic Sclerosis - Patients' and Family Caregivers' Experiences and Expectations of a Specific Education Programme: A Qualitative Study Musculoskeletal Care, March 28, 2013

6 The enhanced liver fibrosis test: a clinical grade, validated serum test, biomarker of overall fibrosis in systemic sclerosis Annals of Rheumatic Diseases, March 25, 2013

7 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013    Evidence Based Medicine

8 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013

9 Can Serum Surfactant Protein D or CC-Chemokine Ligand 18 Predict Outcome of Interstitial Lung Disease in Patients with Early Systemic Sclerosis The Journal of Rheumatology, April 18, 2013

10 Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies Annals of Rheumatic Diseases, April 9, 2013

11 Relation of rheumatoid factor and anti-cyclic citrullinated peptide antibody with disease activity in rheumatoid arthritis: cross-sectional study Rheumatology International, April 26, 2013

12 Interleukin-6: a new therapeutic target in systemic sclerosis Clinical & Translational Immunology, April 19, 2013    Free full text    Review Article

13 Relationship between interleukin-6 and cardiac involvement in systemic sclerosis Rheumatology, April 1, 2013

14 Thrombosis in vasculitis Best Practice & Research Clinical Rheumatology, March 21, 2013    Review Article

15 ESSDAI and ESSPRI: EULAR indexes for a complete picture of primary Sjogrens syndrome patients Arthritis Care & Research , March 6, 2013    Review Article

16 Autoantibodies in Polymyositis and Dermatomyositis Current Rheumatology Reports, April 24, 2013    Review Article

17 Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile Annals of Rheumatic Diseases, April 15, 2013

18 Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases Arthritis Research & Therapy, April 5, 2013    Review Article

19 Anti-citrullinated protein antibodies (ACPA) in unaffected first degree relatives of rheumatoid arthritis patients Arthritis & Rheumatism, March 4, 2013

20 Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results Current Rheumatology Reports, March 22, 2013    Review Article

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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