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Rheumatology - Autoimmune/Heritable News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (3) Full Text Articles (22) Focus on Fibromyalgia461 Superiority of a High Loading Dose of Cholecalciferol to Correct Hypovitaminosis D in Patients with Inflammatory/Autoimmune Rheumatic Diseases The Journal of Rheumatology, December 17, 2012 Clinical Article
462 Interstitial lung disease in anti-jo1 patients with antisynthetase syndrome Arthritis Care & Research , December 17, 2012
463 Headache in primary Sjogrens syndrome: a population-based retrospective cohort study European Journal of Neurology, December 14, 2012
464 Altered functional B-cell subset populations in patients with chronic fatigue syndrome compared to Healthy Controls Clinical and Experimental Immunology, December 14, 2012
465 Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts Rheumatology, December 14, 2012
466 Evaluation of intravenous immunoglobulin resistant and coronary artery lesions by Th1/Th2 cytokine profiles in kawasaki disease Arthritis & Rheumatism, December 14, 2012
467 Hearing loss in Muckle-Wells-syndrome Arthritis & Rheumatism, December 13, 2012
468 Measuring fatigue in SSc: a comparison of the Short Form-36 Vitality subscale and Functional Assessment of Chronic Illness Therapy-Fatigue scale Rheumatology, December 12, 2012
469 Autoantibodies, autoimmune risk alleles and clinical associations in rheumatoid arthritis cases and non-RA controls in the electronic medical records Arthritis & Rheumatism, December 12, 2012
470 The utility of the PHQ-9 to assess suicide risk in patients with systemic sclerosis Arthritis Care & Research , December 11, 2012
471 Follow-up of primary Sjogrens syndrome patients presenting positive anti-cyclic citrullinated peptides antibody Rheumatology International, December 11, 2012
472 Neurosjogren: Early Therapy Is Associated With Successful Outcomes JCR: Journal of Clinical Rheumatology, December 10, 2012
473 Biologics-induced autoimmune diseases Current Opinion in Rheumatology, December 6, 2012
474 Prevalence of Oral Lesions of Autoimmune Etiology in Patients with Primary Sjogrens Syndrome Oral Diseases , December 5, 2012
475 Acro-osteolysis in systemic sclerosis is associated with digital ischaemia and severe calcinosis Rheumatology, December 5, 2012
476 Serum chemokine levels as prognostic markers in patients with early systemic sclerosis: a multicenter, prospective, observational study Modern Rheumatology, December 4, 2012
477 Smoking Is Associated With Reduced Risk of Autoimmune Diabetes in Adults Contrasting With Increased Risk in Overweight Men With Type 2 Diabetes: A 22-year follow-up of the HUNT Study Diabetes Care, December 3, 2012
478 Association between the CD226 rs763361 polymorphism and susceptibility to autoimmune diseases: a meta-analysis Lupus, November 28, 2012
479 Predominant prevalence of arterial thrombosis in Japanese patients with antiphospholipid syndrome Lupus, November 28, 2012
480 Severe optic neuritis in a patient with combined neuromyelitis optica spectrum disease and primary Sjogrens syndrome: a case report Full Text Journal of Medical Case Reports, November 27, 2012
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome Journal of Neural Transmission, May 2, 2013 Review Article
2 The Biological and Clinical Activity of Anti-Malarial Drugs In Autoimmune Disorders Current Rheumatology Reviews, April 19, 2013 Review Article
3 Clinical features distinguishing lymphoma development in primary Sjogrens syndrome--A retrospective cohort study Seminars in Arthritis and Rheumatism, May 10, 2013
4 Efficacy of rituximab in systemic manifestations of primary Sjogrens syndrome: results in 78 patients of the AutoImmune and Rituximab registry Annals of Rheumatic Diseases, May 22, 2013
5 The Immune Response in SAPHO Syndrome: Deficiency, Hyper- Responsiveness, or Both Current Rheumatology Reviews, April 19, 2013 Review Article
6 Use of New Oral Anticoagulants in Antiphospholipid Syndrome Current Rheumatology Reports, May 7, 2013
7 Childhood-onset Eosinophilic Granulomatosis with Polyangiitis (formerly Churg-Strauss Syndrome): A Contemporary Single-center Cohort The Journal of Rheumatology, May 3, 2013
8 Monoclonal anti-TNF antibodies can elevate hemoglobin level in patients with ankylosing spondylitis Rheumatology International, May 28, 2013 Clinical Guideline
9 Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study Annals of Rheumatic Diseases, May 23, 2013 Evidence Based Medicine Review Article
10 Primary Sjogrens syndrome and malignancy risk: a systematic review and meta-analysis Annals of Rheumatic Diseases, May 21, 2013 Evidence Based Medicine Review Article
11 From Sternocostoclavicular Hyperostosis (SCCH) to SAPHO Syndrome Current Rheumatology Reviews, April 19, 2013 Review Article
12 Anti-carbonic anhydrase III autoantibodies in vasculitis syndrome International Journal of Rheumatic Diseases, May 24, 2013 Review Article
13 Neuropsychiatric Lupus: Classification Criteria in Neuroimaging Studies The Canadian Journal of Neurological Sciences, May 9, 2013 Evidence Based Medicine Review Article
14 Seronegative spondyloarthritis and Dariers disease: more than a casual association Rheumatismo, May 28, 2013 Free full text
15 Granulomatosis polyangiitis associated with meningeal involvement: response to rituximab therapy after failure of cyclophosphamide Rheumatismo, May 28, 2013 Free full text
16 Interleukin-7 and its receptor: The axis of evil to target in Sjogrens syndrome Arthritis & Rheumatism, May 14, 2013 Review Article
17 Potential role of adenosine deaminase in the diagnosis of adult-onset Stills disease Rheumatology International, May 3, 2013
18 Changes in biomarkers after therapeutic intervention in temporal arteries cultured in Matrigel: a new model for preclinical studies in giant-cell arteritis Annals of Rheumatic Diseases, May 7, 2013
19 Osteoimmunology and bone homeostasis: relevance to spondyloarthritis Current Rheumatology Reports, May 30, 2013 Review Article
20 Crosstalk between inflammation, iron metabolism and endotelial function in Behcets disease Clinical Hemorheology and Microcirculation, May 1, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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