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Rheumatology - Gout and Hyperuricemia News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest Full Text Articles (18) Focus on Osteoporosis
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

241 Cytokine levels in human synovial fluid during the different stages of acute gout: Role of transforming growth factor {beta}1 in the resolution phase Annals of Rheumatic Diseases, February 7, 2012

242 Effects of skim milk powder enriched with glycomacropeptide and G600 milk fat extract on frequency of gout flares: A proof-of-concept randomized controlled trial Annals of Rheumatic Diseases, February 7, 2012    Clinical Article

243 Use of diuretics and the risk of gouty arthritis: A systematic review Seminars in Arthritis and Rheumatism, February 6, 2012    Clinical Article

244 Effects of SLC2A9 variants on uric acid levels in a Korean population Rheumatology International, January 27, 2012

245 Gout and Organ Transplantation Current Rheumatology Reports, January 24, 2012

246 National prevalence of gout derived from administrative health data in Aotearoa New Zealand Rheumatology, January 23, 2012

247 Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction Full Text Arthritis Research & Therapy, January 19, 2012

248 P2Y6 Receptor Signaling Pathway Mediates Inflammatory Responses Induced by Monosodium Urate Crystals Full Text The Journal of Immunology, January 13, 2012

249 Disability due to gouty arthritis Current Opinion in Rheumatology, January 13, 2012

250 Mechanisms of joint damage in gout: evidence from cellular and imaging studies Nature Reviews Rheumatology , January 12, 2012

251 Ultrasound characteristics of gouty tophi in the olecranon bursa and evaluation of their reproducibility European Journal of Radiology, January 12, 2012

252 Rilonacept (IL-1 Trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a Phase 2 clinical trial Arthritis & Rheumatism, January 11, 2012

253 Association between being African-American, serum urate levels, and the risk of developing hyperuricemia: findings from the coronary artery risk development in young adults (CARDIA) cohort Full Text Arthritis Research & Therapy, January 10, 2012

254 Markers of systemic inflammation in children with hyperuricemia Acta Pediatrica, January 6, 2012

255 Recent advances in management of gout QJM: An International Journal of Medicine, January 3, 2012    Clinical Article

256 Assessment of Tophus Size: A Comparison Between Physical Measurement Methods and Dual-Energy Computed Tomography Scanning JCR: Journal of Clinical Rheumatology, December 27, 2011

257 Treatment and management of pseudogout: insights for the clinician Therapeutic Advances in Musculoskeletal Disease, December 26, 2011

258 The Patients Experience of Gout: New Insights to Optimize Management Current Rheumatology Reports, December 26, 2011

259 Mortality due to coronary heart disease and kidney disease among middle-aged and elderly men and women with gout in the Singapore Chinese Health Study Annals of Rheumatic Diseases, December 22, 2011
Exclusive Author Commentary

260 The epidemiology and treatment of gout Full Text Open Access Rheumatology: Research and Reviews, December 22, 2011

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Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality QJM: An International Journal of Medicine, April 11, 2013

2 New developments in gout Current Opinion in Rheumatology, March 29, 2013

3 Gout, stone composition and urinary stone risk: a matched case comparative study The Journal of Urology, April 4, 2013

4 Ultrasound learning curve in gout: A disease-oriented training programme Arthritis Care & Research , April 1, 2013

5 Role of Interleukin-1 Inhibitors in the Management of Gout Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 5, 2013

6 Urate lowering therapies: an overview Journal de Pharmacie Clinique, March 25, 2013

7 A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study Annals of Rheumatic Diseases, April 8, 2013

8 Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study Annals of Rheumatic Diseases, April 10, 2013

9 Uric Acid Levels Correlate with Baseline Renal Function and High Levels are a Potent Risk Factor for Postoperative Chronic Kidney Disease in Patients with Renal Cell Carcinoma The Journal of Urology, April 16, 2013

10 Italian Society of Rheumatology recommendations for the management of gout Rheumatismo, April 3, 2013    Free full text

11 A systematic review of ultrasonography in gout and asymptomatic hyperuricaemia Annals of Rheumatic Diseases, April 9, 2013    Evidence Based Medicine

12 New classification criteria for gout: a framework for progress Rheumatology, April 24, 2013

13 Management of Gouty Arthritis in Patients With Chronic Kidney Disease American Journal of Therapeutics, March 27, 2013

14 Allopurinol Hypersensitivity Reactions: Desensitization Strategies and New Therapeutic Alternative Molecules Inflammation & Allergy - Drug Targets, April 12, 2013

15 Extent and distribution of CPP deposits in patients affected by calcium pyrophosphate dihydrate deposition disease: an ultrasonographic study Annals of Rheumatic Diseases, April 11, 2013

16 Lipid-Associated Rheumatologic Syndromes Rheumatic Disease Clinics of North America, April 23, 2013    Review Article

17 Understanding the dose-response relationship of allopurinol: predicting the optimal dosage British Journal of Clinical Pharmacology, April 22, 2013
Exclusive Author Commentary

18 Hyperuricemia, and nutritional ways to approach it Journal de Pharmacie Clinique, March 21, 2013

19 Primary care providers knowledge, beliefs and treatment practices for gout: results of a physician questionnaire Rheumatology, April 29, 2013

20 Gout treatment: should we aim for rapid crystal dissolution Annals of Rheumatic Diseases, April 8, 2013

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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