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Rheumatology - Gout and Hyperuricemia News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest Full Text Articles (18) Focus on Fibromyalgia
181
Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study
Annals of Rheumatic Diseases, July 9, 2012
Exclusive Author Commentary
182 Clinical Consequences of Mutations in Sodium Phosphate Cotransporters Clinical Journal of the American Society of Nephrology, July 9, 2012
183 Enhanced interleukin-1beta production of peripheral blood mononuclear cells from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals Full Text Arthritis Research & Therapy, July 6, 2012
184 Association of uric acid with mortality in patients with stable coronary artery disease Metabolism, July 5, 2012
185 Critical appraisal of the role of pegloticase in the management of gout Full Text Open Access Rheumatology: Research and Reviews, June 28, 2012 Clinical Article
186 Incident Gout in Women and Association with Obesity in the Atherosclerosis Risk in Communities (ARIC) Study American Journal of Medicine, June 27, 2012 Clinical Article
187 Comorbidities of Gout and Hyperuricemia in the US General Population: NHANES 2007-2008 American Journal of Medicine, June 26, 2012
188 Patients with gout adhere to curative treatment if informed appropriately: proof-of-concept observational study Annals of Rheumatic Diseases, June 26, 2012
189 Potential unmet need for gout diagnosis and treatment: capture–recapture analysis of a national administrative dataset Rheumatology, June 25, 2012
190 Hypertension and the risk of incident gout in a population-based study: the atherosclerosis risk in communities cohort The Journal of Clinical Hypertension, June 20, 2012
191 Cardiovascular safety of febuxostat and allopurinol in patients with gout and cardiovascular comorbidities American Heart Journal, June 18, 2012 Clinical Article
192 Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid Full Text Nutrition Journal, June 15, 2012
193 Colchicine Use Is Associated with Decreased Prevalence of Myocardial Infarction in Patients with Gout The Journal of Rheumatology, June 7, 2012 Clinical Article
194 Purine-rich foods intake and recurrent gout attacks Annals of Rheumatic Diseases, June 7, 2012
195 Improved Health-related Quality of Life and Physical Function in Patients with Refractory Chronic Gout Following Treatment with Pegloticase: Evidence from Phase III Randomized Controlled Trials The Journal of Rheumatology, June 5, 2012 Clinical Article
196 Uric acid concentration as a risk marker for blood pressure progression and incident hypertension : A Chinese cohort study Metabolism, June 5, 2012
197 Effect of uric acid lowering therapy on the prevention of acute kidney injury in cardiovascular surgery International Urology and Nephrology, June 4, 2012 Clinical Article
198 The role of uric acid in the pathogenesis of hypertension in the young The Journal of Clinical Hypertension, June 1, 2012
199 Serum uric acid is related to cardiovascular events and correlates with N-terminal pro-B-type natriuretic peptide and albuminuria in patients with diabetes mellitus Diabetic Medicine, May 30, 2012
200 Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions Annals of Rheumatic Diseases, May 24, 2012 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality QJM: An International Journal of Medicine, April 11, 2013
2 New developments in gout Current Opinion in Rheumatology, March 29, 2013
3 Gout, stone composition and urinary stone risk: a matched case comparative study The Journal of Urology, April 4, 2013
4 Ultrasound learning curve in gout: A disease-oriented training programme Arthritis Care & Research , April 1, 2013
5 Role of Interleukin-1 Inhibitors in the Management of Gout Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 5, 2013
6 Urate lowering therapies: an overview Journal de Pharmacie Clinique, March 25, 2013
7 A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study Annals of Rheumatic Diseases, April 8, 2013
8 Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study Annals of Rheumatic Diseases, April 10, 2013
9 Uric Acid Levels Correlate with Baseline Renal Function and High Levels are a Potent Risk Factor for Postoperative Chronic Kidney Disease in Patients with Renal Cell Carcinoma The Journal of Urology, April 16, 2013
10 Italian Society of Rheumatology recommendations for the management of gout Rheumatismo, April 3, 2013 Free full text
11 A systematic review of ultrasonography in gout and asymptomatic hyperuricaemia Annals of Rheumatic Diseases, April 9, 2013 Evidence Based Medicine
12 New classification criteria for gout: a framework for progress Rheumatology, April 24, 2013
13 Management of Gouty Arthritis in Patients With Chronic Kidney Disease American Journal of Therapeutics, March 27, 2013
14 Allopurinol Hypersensitivity Reactions: Desensitization Strategies and New Therapeutic Alternative Molecules Inflammation & Allergy - Drug Targets, April 12, 2013
15 Extent and distribution of CPP deposits in patients affected by calcium pyrophosphate dihydrate deposition disease: an ultrasonographic study Annals of Rheumatic Diseases, April 11, 2013
16 Lipid-Associated Rheumatologic Syndromes Rheumatic Disease Clinics of North America, April 23, 2013 Review Article
17
Understanding the dose-response relationship of allopurinol: predicting the optimal dosage
British Journal of Clinical Pharmacology, April 22, 2013
Exclusive Author Commentary
18 Hyperuricemia, and nutritional ways to approach it Journal de Pharmacie Clinique, March 21, 2013
19 Primary care providers knowledge, beliefs and treatment practices for gout: results of a physician questionnaire Rheumatology, April 29, 2013
20 Gout treatment: should we aim for rapid crystal dissolution Annals of Rheumatic Diseases, April 8, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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