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Rheumatology - Connective Tissue Dz News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

  • Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
  • MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

Your Unread Messages in Rheumatology

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Articles

Latest (3) Full Text Articles (5) Focus on Gout
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Lung Involvement in Connective Tissue Diseases: A Comprehensive Review and A Focus On Rheumatoid Arthritis Autoimmunity Reviews, May 17, 2013    Clinical Article

2 Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of Systemic Sclerosis and Sjogren’s Syndrome Autoimmunity Reviews, May 17, 2013    Clinical Article

3 Case of diffuse cutaneous systemic sclerosis with anti-Ku and anti-centromere antibodies The Journal of Dermatology, May 17, 2013

Prior Articles

4 Systemic Sclerosis in Canada's North American Native Population: Assessment of Clinical and Serological Manifestations The Journal of Rheumatology, May 16, 2013    Clinical Article

5 Systemic sclerosis patients with and without pulmonary arterial hypertension: a nailfold capillaroscopy study Rheumatology, May 15, 2013    Clinical Article

6 Anti-CADM-140/MDA5 autoantibody titer correlates with disease activity and predicts disease outcome in patients with dermatomyositis and rapidly progressive interstitial lung disease Modern Rheumatology, May 15, 2013    Clinical Article

7 Interleukin-7 and its receptor: The axis of evil to target in Sjogrens syndrome Arthritis & Rheumatism, May 14, 2013    Review Article

8 Systemic sclerosis sine scleroderma: distinct features in a large Brazilian cohort Rheumatology, May 14, 2013    Clinical Article

9 Four-year-olds, healthy or recovering from Juvenile Dermatomyositis, do not achieve a full score on the Childhood Myositis Assessment Scale (CMAS) Arthritis Care & Research , May 14, 2013    Clinical Article

10 Mortality factors in idiopathic inflammatory myopathy: focusing on malignancy and interstitial lung disease Modern Rheumatology, May 14, 2013    Review Article    Clinical Article

11 Systemic sclerosis and the gut Expert Review of Gastroenterology & Hepatology, May 13, 2013    Review Article

12 Clinical features distinguishing lymphoma development in primary Sjogrens syndrome--A retrospective cohort study Seminars in Arthritis and Rheumatism, May 10, 2013    Clinical Article

13 Evaluation of a mail-delivered, print-format, self-management program for persons with systemic sclerosis Clinical Rheumatology, May 10, 2013    Clinical Article

14 HMGA2-IGF2BP2 Regulates NRAS in Rhabdomyosarcoma Cancer Research, May 10, 2013    Review Article

15 Correlations between nailfold microangiopathy severity, finger dermal thickness and fingertip blood perfusion in systemic sclerosis patients Annals of Rheumatic Diseases, May 8, 2013    Clinical Article

16 Punctal plugs versus artificial tears for treating primary Sjogrens syndrome with keratoconjunctivitis SICCA: a comparative observation of their effects on visual function Rheumatology International, May 7, 2013    Clinical Article

17 Survival and Causes of Death in an Unselected and Complete Cohort of Norwegian Patients with Systemic Sclerosis The Journal of Rheumatology, May 6, 2013    Review Article

18 Recurrent Compartment Syndrome in a Patient With Clinical Features of a Connective Tissue Disorder American Journal of Medical Genetics Part A, May 6, 2013

19 Capillaroscopic Skin Ulcers Risk Index (CSURI) calculated with different videocapillaroscopy devices: how its predictive values change Clinical and Experimental Rheumatology Online, May 3, 2013    Clinical Article

20 Incidence of scleroderma spectrum disorders in Slovenia Clinical and Experimental Rheumatology Online, May 3, 2013    Review Article

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Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013

2 Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies Arthritis & Rheumatism, April 11, 2013    Evidence Based Medicine

3 Sarcoidosis and Sjogrens syndrome: clinical and salivary evaluation Journal of Oral Pathology & Medicine, March 27, 2013    Review Article

4 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013    Evidence Based Medicine

5 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013    Free full text

6 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013

7 Skin and Mucosa Care in Systemic Sclerosis - Patients' and Family Caregivers' Experiences and Expectations of a Specific Education Programme: A Qualitative Study Musculoskeletal Care, March 28, 2013

8 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013

9 Anti B-cell therapy against refractory thrombocytopenia in SLE and MCTD patients: long-term follow-up and review of the literature Lupus, April 25, 2013

10 Mycophenolate Mofetil Improves Lung Function in Connective Tissue Disease-associated Interstitial Lung Disease The Journal of Rheumatology, March 6, 2013

11 Relationship between interleukin-6 and cardiac involvement in systemic sclerosis Rheumatology, April 1, 2013

12 Cryofibrinogenemia JCR: Journal of Clinical Rheumatology, March 29, 2013    Review Article

13 No association of primary Sjögren’s syndrome with Fcγ receptor gene variants Genes and Immunity, April 12, 2013    Review Article

14 Undifferentiated connective tissue disease in a rheumatology center in Cali, Colombia: clinical features of 94 patients followed for a year Rheumatology International, April 8, 2013

15 Rationale for treating primary Sjogrens syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab) Immunologic Research, April 26, 2013    Review Article

16 Rheumatic manifestations in primary hypothyroidism Indian Journal of Rheumatology , March 28, 2013

17 Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results Current Rheumatology Reports, March 22, 2013    Review Article

18 Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Arthritis Research & Therapy, April 5, 2013

19 Assessment of left ventricular functions in patients with Sjogrens syndrome using tissue doppler echocardiography International Journal of Rheumatic Diseases, April 11, 2013

20 Functional articular cartilage repair: here, near, or is the best approach not yet clear Nature Reviews Rheumatology , March 20, 2013    Review Article

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Other Topics in Rheumatology

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