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Rheumatology - Connective Tissue Dz News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (2) Full Text Articles (5) Focus on Osteoporosis981 Nerve conduction studies in patients with dermatomyositis or polymyositis Full Text Chinese Medical Journal, March 16, 2010
982 Reverse-namaskar: A new sign in Ehlers-Danlos syndrome: A family pedigree study of four generations Full Text Indian Journal of Dermatology, March 16, 2010
983 Age-related survival and clinical features in systemic sclerosis patients older or younger than 65 at diagnosis Rheumatology, March 15, 2010
984 Systemic Sclerosis-associated Pulmonary Arterial Hypertension Full Text American Journal of Respiratory and Critical Care Medicine, March 11, 2010
985 Innovative therapies for systemic sclerosis Current Opinion in Rheumatology, March 10, 2010
986 Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials? Rheumatology, March 8, 2010 Clinical Article
987 Early detection of cardiac involvement in systemic sclerosis assessed by tissue-doppler echocardiography: Relationship with neurohormonal activation and endothelial dysfunction The Journal of Rheumatology, March 4, 2010
988 Similarities and differences between primary and secondary Sjogren's syndrome The Journal of Rheumatology, March 4, 2010 Clinical Article
989 Thumb involvement in Raynaud's phenomenon as an indicator of underlying connective tissue disease The Journal of Rheumatology, March 4, 2010
990 Antagonistic Effect of the Matricellular Signaling Protein CCN3 on TGF-beta- and Wnt-Mediated Fibrillinogenesis in Systemic Sclerosis and Marfan Syndrome Full Text Journal of Investigative Dermatology, March 1, 2010
991 Renal disease in systemic sclerosis with normal serum creatinine Clinical Rheumatology, February 26, 2010 Clinical Article
992 Association of the FAM167A-BLK region with systemic sclerosis Arthritis & Rheumatism, February 26, 2010
993 Clinical associations with autoantibody reactivities to individual components of U1 small nuclear ribonucleoprotein Lupus, February 25, 2010
994 Therapeutic angiogenesis in patients with systemic sclerosis by autologous transplantation of bone-marrow-derived cells Modern Rheumatology, February 23, 2010 Clinical Article
995 Etanercept-induced anti-Jo-1-antibody-positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature Clinical Rheumatology, February 23, 2010
996 Employment status and socio-economic burden in systemic sclerosis: A cross-sectional survey Rheumatology, February 22, 2010 Clinical Article
997 Elevated serum concentrations of triggering receptor expressed on myeloid cells-1 in diffuse cutaneous systemic sclerosis: Association with severity of pulmonary fibrosis The Journal of Rheumatology, February 18, 2010
998 Lack of effect of 8 weeks atorvastatin on microvascular endothelial function in patients with systemic sclerosis Rheumatology, February 18, 2010 Clinical Article
999 Rare connective tissue disorders Paediatrics and Child Health, February 17, 2010
1000 Transitional care for young people with connective tissue diseases Paediatrics and Child Health, February 17, 2010
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
2 Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies Arthritis & Rheumatism, April 11, 2013 Evidence Based Medicine
3 Sarcoidosis and Sjogrens syndrome: clinical and salivary evaluation Journal of Oral Pathology & Medicine, March 27, 2013 Review Article
4 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
5 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
6 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013
7 Skin and Mucosa Care in Systemic Sclerosis - Patients' and Family Caregivers' Experiences and Expectations of a Specific Education Programme: A Qualitative Study Musculoskeletal Care, March 28, 2013
8 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
9 Anti B-cell therapy against refractory thrombocytopenia in SLE and MCTD patients: long-term follow-up and review of the literature Lupus, April 25, 2013
10 Mycophenolate Mofetil Improves Lung Function in Connective Tissue Disease-associated Interstitial Lung Disease The Journal of Rheumatology, March 6, 2013
11 Relationship between interleukin-6 and cardiac involvement in systemic sclerosis Rheumatology, April 1, 2013
12 Cryofibrinogenemia JCR: Journal of Clinical Rheumatology, March 29, 2013 Review Article
13 No association of primary Sjögren’s syndrome with Fcγ receptor gene variants Genes and Immunity, April 12, 2013 Review Article
14 Undifferentiated connective tissue disease in a rheumatology center in Cali, Colombia: clinical features of 94 patients followed for a year Rheumatology International, April 8, 2013
15 Rationale for treating primary Sjogrens syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab) Immunologic Research, April 26, 2013 Review Article
16 Rheumatic manifestations in primary hypothyroidism Indian Journal of Rheumatology , March 28, 2013
17 Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results Current Rheumatology Reports, March 22, 2013 Review Article
18 Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Arthritis Research & Therapy, April 5, 2013
19 Assessment of left ventricular functions in patients with Sjogrens syndrome using tissue doppler echocardiography International Journal of Rheumatic Diseases, April 11, 2013
20 Functional articular cartilage repair: here, near, or is the best approach not yet clear Nature Reviews Rheumatology , March 20, 2013 Review Article
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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