Rheumatology - Connective Tissue Dz News & Articles

What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content

Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

41 Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion Arthritis Research & Therapy, April 19, 2013 Clinical Article

42 Clinical correlation of brachial artery flow-mediated dilation in patients with systemic sclerosis Modern Rheumatology, April 19, 2013 Clinical Article

43 The Biological and Clinical Activity of Anti-Malarial Drugs In Autoimmune Disorders Current Rheumatology Reviews, April 19, 2013 Review Article Clinical Article

44 Can Serum Surfactant Protein D or CC-Chemokine Ligand 18 Predict Outcome of Interstitial Lung Disease in Patients with Early Systemic Sclerosis The Journal of Rheumatology, April 18, 2013 Clinical Article

45 Novel aspects of Sjogren's syndrome in 2012 Full Text BMC Medicine, April 16, 2013 Clinical Article

46 Association of Gastroesophageal Factors and Worsening of Forced Vital Capacity in Systemic Sclerosis The Journal of Rheumatology, April 15, 2013 Review Article

47 Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogrens syndrome and association with disease activity and BAFF gene expression Annals of Rheumatic Diseases, April 15, 2013 Review Article

48 The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis Annals of Rheumatic Diseases, April 15, 2013 Review Article

49 No association of primary Sjögren’s syndrome with Fcγ receptor gene variants Genes and Immunity, April 12, 2013 Review Article

50 Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies Arthritis & Rheumatism, April 11, 2013 Evidence Based Medicine Clinical Article

51 Assessment of left ventricular functions in patients with Sjogrens syndrome using tissue doppler echocardiography International Journal of Rheumatic Diseases, April 11, 2013 Clinical Article

52 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013 Clinical Article

53 MRI guided wire localization muscle biopsy in a child with juvenile dermatomyositis Pediatric Rheumatology, April 9, 2013

54 Undifferentiated connective tissue disease in a rheumatology center in Cali, Colombia: clinical features of 94 patients followed for a year Rheumatology International, April 8, 2013 Clinical Article

55 Skin ulcer is a predictive and prognostic factor of acute or subacute interstitial lung disease in dermatomyositis Rheumatology International, April 8, 2013 Clinical Article

56 Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Arthritis Research & Therapy, April 5, 2013 Clinical Article

57 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013 Clinical Article

58 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013 Clinical Article

59 A Delphi exercise and cluster analysis to aid in the development of potential classification criteria for systemic sclerosis (SSc) using SSc experts and databases Clinical and Experimental Rheumatology Online, April 3, 2013 Clinical Article

60 Late appearance and exacerbation of primary Raynauds phenomenon attacks can predict future development of connective tissue disease: a retrospective chart review of 3,035 patients Rheumatology International, April 3, 2013 Clinical Article

50 available pages First Previous 3 4 5 6 7 8 9 10 11 12 Next Last

Clinical Pearls in Rheumatology

Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.

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Predicting cardiovascular mortality in SLE

In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.

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Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.

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Most Popular Rheumatology Articles

Last month's top read Top Articles of 2012

1 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013

2 Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies Arthritis & Rheumatism, April 11, 2013 Evidence Based Medicine

3 Sarcoidosis and Sjogrens syndrome: clinical and salivary evaluation Journal of Oral Pathology & Medicine, March 27, 2013 Review Article

4 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine

5 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text

6 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013

7 Skin and Mucosa Care in Systemic Sclerosis - Patients' and Family Caregivers' Experiences and Expectations of a Specific Education Programme: A Qualitative Study Musculoskeletal Care, March 28, 2013

8 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013

9 Anti B-cell therapy against refractory thrombocytopenia in SLE and MCTD patients: long-term follow-up and review of the literature Lupus, April 25, 2013

10 Mycophenolate Mofetil Improves Lung Function in Connective Tissue Disease-associated Interstitial Lung Disease The Journal of Rheumatology, March 6, 2013

11 Relationship between interleukin-6 and cardiac involvement in systemic sclerosis Rheumatology, April 1, 2013

12 Cryofibrinogenemia JCR: Journal of Clinical Rheumatology, March 29, 2013 Review Article

13 No association of primary Sjögren’s syndrome with Fcγ receptor gene variants Genes and Immunity, April 12, 2013 Review Article

14 Undifferentiated connective tissue disease in a rheumatology center in Cali, Colombia: clinical features of 94 patients followed for a year Rheumatology International, April 8, 2013

15 Rationale for treating primary Sjogrens syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab) Immunologic Research, April 26, 2013 Review Article

16 Rheumatic manifestations in primary hypothyroidism Indian Journal of Rheumatology , March 28, 2013

17 Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results Current Rheumatology Reports, March 22, 2013 Review Article

18 Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Arthritis Research & Therapy, April 5, 2013

19 Assessment of left ventricular functions in patients with Sjogrens syndrome using tissue doppler echocardiography International Journal of Rheumatic Diseases, April 11, 2013

20 Functional articular cartilage repair: here, near, or is the best approach not yet clear Nature Reviews Rheumatology , March 20, 2013 Review Article

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more

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Rheumatology - Connective Tissue Dz News & Articles

Articles

Clinical Pearls in Rheumatology

Highlights in Rheumatology

ACPA correlate with disease progression in JIA

Predicting cardiovascular mortality in SLE

Anti-apoA-1 antibodies predict cardiovascular disease in RA patients

Most Popular Rheumatology Articles

Other Topics in Rheumatology