- Home
- Your Messages
-
Smartest Doc
Daily Quiz CompetitionTest your clinical knowledge against other physicians in the USA by taking our FREE daily quiz!
New! PHYSICIAN REVIEW
Thousands of questions to assess your knowledge and aid exam prep!
- Physician Jobs (602)
- More
- Other Specialty
Rheumatology - Connective Tissue Dz News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
See All >> Messages include industry-sponsored communications and special communications from MDLinx-
D Scott Cunningham MD, PhD
Site Editor, MDLinx
Hypovitaminosis D common in SLE -
Jill Baker
MDLinx Career Center
NPs and PAs play crucial role amid PCP shortage -
Smartest Doc Challenge
MDLinx
Clinical Pearls for Rheumatologists -
MDLinx Reminder
MDLinx
Conference Center Upgraded with New Tools -
MDLinx Top Read
MDLinx
Running from that pile of unread journals?
Articles
Latest Full Text Articles (5) Focus on Osteoporosis441 Interleukin 6 in Systemic Sclerosis and Potential Implications for Targeted Therapy The Journal of Rheumatology, April 18, 2012
442 Effect of Gastrointestinal Manifestations on Quality of Life in 87 Consecutive Patients with Systemic Sclerosis The Journal of Rheumatology, April 16, 2012
443 IRF5 polymorphism predicts prognosis in patients with systemic sclerosis Annals of Rheumatic Diseases, April 16, 2012
444 Increased serum levels of soluble CD163 in patients with scleroderma Clinical Rheumatology, April 13, 2012
445 Impaired IL-17 Signaling Pathway Contributes to the Increased Collagen Expression in Scleroderma Fibroblasts The Journal of Immunology, April 12, 2012
446 Positivity for anti-RNP antibody is a risk factor for adverse effects caused by trimethoprim-sulfamethoxazole, a prophylactic agent for P. jiroveci pneumonia, in patients with connective tissue diseases Modern Rheumatology, April 11, 2012
447 Evaluation of a new multi-parallel line immunoassay for systemic sclerosis-associated antibodies in an Asian population Rheumatology, April 10, 2012
448 Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis Full Text Arthritis Research & Therapy, April 9, 2012
449 A Prospective Observational Study of Mycophenolate Mofetil Treatment in Progressive Diffuse Cutaneous Systemic Sclerosis of Recent Onset The Journal of Rheumatology, April 5, 2012
450 Independent Replication and Metaanalysis of Association Studies Establish TNFSF4 as a Susceptibility Gene Preferentially Associated with the Subset of Anticentromere-positive Patients with Systemic Sclerosis The Journal of Rheumatology, April 5, 2012 Evidence Based Medicine
451 Systemic sclerosis disease modification clinical trials design: Quo vadis? Arthritis Care & Research , April 5, 2012
452 Treatment of Systemic Sclerosis Complications: What to Use When First-Line Treatment Fails-A Consensus of Systemic Sclerosis Experts Seminars in Arthritis and Rheumatism, April 4, 2012
453 Supernatants from culture of type I collagen-stimulated PBMC from patients with cutaneous systemic sclerosis versus localized scleroderma demonstrate suppression of MMP-1 by fibroblasts Clinical Rheumatology, April 4, 2012
454 The influence of measurement location on reliability of quantitative nailfold videocapillaroscopy in patients with SSc Rheumatology, April 2, 2012
455 Positive association between STAT4 polymorphisms and polymyositis/dermatomyositis in a Japanese population Annals of Rheumatic Diseases, April 2, 2012
456 Influence of somatic symptoms on PHQ-9 depression scores among patients with systemic sclerosis compared to a healthy general population sample Arthritis Care & Research , March 30, 2012
457 Evaluation of Chronic Kidney Disease Epidemiology Collaboration equation to estimate glomerular filtration rate in scleroderma patients Rheumatology, March 30, 2012
458 Validation of potential classification criteria for systemic sclerosis Arthritis Care & Research , March 27, 2012
459 The Association of Illness Perceptions with Physical and Mental Health in Systemic Sclerosis Patients: An Exploratory Study Musculoskeletal Care, March 26, 2012
460 A clinical decision rule to predict the presence of interstitial lung disease in systemic sclerosis Arthritis Care & Research , March 23, 2012
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
2 Cancer incidence in systemic sclerosis: Meta-analysis of population-based cohort studies Arthritis & Rheumatism, April 11, 2013 Evidence Based Medicine
3 Sarcoidosis and Sjogrens syndrome: clinical and salivary evaluation Journal of Oral Pathology & Medicine, March 27, 2013 Review Article
4 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
5 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
6 Risk factors for body composition abnormalities in systemic sclerosis Clinical Rheumatology, April 4, 2013
7 Skin and Mucosa Care in Systemic Sclerosis - Patients' and Family Caregivers' Experiences and Expectations of a Specific Education Programme: A Qualitative Study Musculoskeletal Care, March 28, 2013
8 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
9 Anti B-cell therapy against refractory thrombocytopenia in SLE and MCTD patients: long-term follow-up and review of the literature Lupus, April 25, 2013
10 Mycophenolate Mofetil Improves Lung Function in Connective Tissue Disease-associated Interstitial Lung Disease The Journal of Rheumatology, March 6, 2013
11 Relationship between interleukin-6 and cardiac involvement in systemic sclerosis Rheumatology, April 1, 2013
12 Cryofibrinogenemia JCR: Journal of Clinical Rheumatology, March 29, 2013 Review Article
13 No association of primary Sjögren’s syndrome with Fcγ receptor gene variants Genes and Immunity, April 12, 2013 Review Article
14 Undifferentiated connective tissue disease in a rheumatology center in Cali, Colombia: clinical features of 94 patients followed for a year Rheumatology International, April 8, 2013
15 Rationale for treating primary Sjogrens syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab) Immunologic Research, April 26, 2013 Review Article
16 Rheumatic manifestations in primary hypothyroidism Indian Journal of Rheumatology , March 28, 2013
17 Update on Stem Cell Transplantation for Systemic Sclerosis: Recent Trial Results Current Rheumatology Reports, March 22, 2013 Review Article
18 Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Arthritis Research & Therapy, April 5, 2013
19 Assessment of left ventricular functions in patients with Sjogrens syndrome using tissue doppler echocardiography International Journal of Rheumatic Diseases, April 11, 2013
20 Functional articular cartilage repair: here, near, or is the best approach not yet clear Nature Reviews Rheumatology , March 20, 2013 Review Article
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
Register now to view all the MDLinx contents (FREE)!
- Stay current on the latest literature, research and clinical news
- Get special communications and offers from MDLinx and our sponsors
- Receive invitations to paid market research
Login
Stay current - Media Tool
♦ Subscribe to our free RSS feeds:
Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More ♦
♦ Follow Us on Twitter
Twitter is a rich source of instantly updated information. Join today and follow @MDLinx to start receiving tweets. Learn More ♦
Close