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Rheumatology - Amyloidosis News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (2) Full Text Articles (17) Focus on Rheumatoid Arthritis361 Tracheal amyloidosis-an unusual cause of stridor ENT Journal, June 4, 2009
362 Cardiac Amyloidosis Treated with an Implantable Cardioverter Defibrillator and Subcutaneous Array Lead System: Report of a Case and Literature Review Clinical Cardiology, May 28, 2009
363 Tocilizumab dramatically ameliorated life-threatening diarrhea due to secondary amyloidosis associated with rheumatoid arthritis Clinical Rheumatology, May 21, 2009
364 Intracardiac Thrombosis and Anticoagulation Therapy in Cardiac Amyloidosis Full Text Circulation, May 15, 2009
365 Febrile reactions occurring with second cycle of high-dose melphalan and SCT in patients with AL amyloidosis Bone Marrow Transplantation, May 8, 2009
366 Novel treatments for systemic amyloidosis International Journal of Clinical Rheumatology, May 7, 2009
367 Clinical outcome of immunoglobulin light chain amyloidosis affecting the kidney Nephrology Dialysis Transplantation, May 6, 2009
368 Isolated Laryngo-tracheal Amyloidosis Presenting as a Refractory Asthma and Longstanding Hoarseness Journal of Asthma, April 29, 2009
369 New therapeutic strategy for amyloidosis Full Text Future Neurology, April 27, 2009
370 Familial Mediterranean Fever: A review for clinical management Joint, Bone, Spine, April 23, 2009
371 Fixed digital contractures revealing light-chain amyloidosis Joint, Bone, Spine, April 21, 2009
372 Prevalence of subclinical amyloidosis in Tunisian patients with rheumatoid arthritis Joint, Bone, Spine, April 15, 2009
373 The acute-phase response protein serum amyloid A stimulates renal tubule formation: studies in vitro and in vivo American Journal of Physiology: Renal Physiology, April 8, 2009
374 Amyloidosis—Recent Developments Seminars in Arthritis and Rheumatism, March 31, 2009
375 Primary localized cutaneous amyloidosis: a sign of immune dysregulation International Journal of Dermatology, March 30, 2009
376 Doppler myocardial imaging compared to standard two-dimensional and doppler echocardiography for assessment of diastolic function in patients with systemic amyloidosis Journal of the American Society of Echocardiography, March 24, 2009 Clinical Article
377 Nanobiotechnology for the Prevention of Dialysis-related Amyloidosis Therapeutic Apheresis and Dialysis, March 17, 2009
378 Doppler myocardial imaging compared to standard two-dimensional and doppler echocardiography for assessment of diastolic function in patients with systemic amyloidosis Journal of The American Society of Echocardiography, March 11, 2009
379 Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis Full Text Haematologica, March 4, 2009
380 Primary (AL) amyloidosis with gastrointestinal involvement Scandinavian Journal of Gastroenterology, February 26, 2009 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Revisiting secondary amyloidosis for an inadequately investigated feature: dyslipidemia Rheumatology International, April 4, 2013 Review Article
2 Atomic structure and hierarchical assembly of a cross-β amyloid fibril Proceedings of the National Academy of Sciences of the United States of America, April 8, 2013 Review Article
3
Cardioverter-defibrillator implantation in myeloma-associated cardiac amyloidosis
Experimental and Clinical Cardiology, April 2, 2013
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Exclusive Author Commentary
4 The role of amyloid β in the pathogenesis of Alzheimers disease Journal of Clinical Pathology, April 11, 2013
5 Pediatric Extranodal Marginal Zone B-Cell Lymphoma Presenting as Amyloidosis in Minor Salivary Glands: A Case Report and Review of the Literature Journal of Pediatric Hematology/Oncology, April 3, 2013 Review Article
6 Is Verbal Episodic Memory in Elderly with Amyloid Deposits Preserved Through Altered Neuronal Function Cerebral Cortex, April 9, 2013
7 Oral health and oral quality of life in inactive patients with familial Mediterranean fever without amyloidosis Clinical and Experimental Rheumatology Online, April 3, 2013
8 Comparison of cardiac amyloidosis due to wild-type and V122I transthyretin in older adults referred to an academic medical center Aging Health, April 9, 2013 Review Article
9 Recent advances in the management of children with familial Mediterranean fever International Journal of Clinical Rheumatology, April 3, 2013
10 Mass spectrometry based proteomics in the diagnosis of kidney disease Current Opinion in Nephrology and Hypertension, April 19, 2013
11 Itch in familial lichen amyloidosis: effective treatment with amitriptyline in two cases Dermatologic Therapy, March 28, 2013
12 Evaluation of domino liver transplantations in Germany Transplant International, April 17, 2013 Review Article
13 Mean platelet volume as a potential predictor of proteinuria and amyloidosis in familial Mediterranean fever Clinical Rheumatology, April 23, 2013 Review Article
14 Noncontrast T1 Mapping for the Diagnosis of Cardiac Amyloidosis JACC Cardiovascular Imaging, April 12, 2013
15 Thalidomide improves clinical symptoms of primary cutaneous amyloidosis: report of familiar and sporadic cases Dermatologic Therapy, March 18, 2013
16 Immunoglobulin light chain amyloidosis: 2013 update on diagnosis, prognosis, and treatment American Journal of Hematology, April 22, 2013
17 Aliphatic peptides show similar self-assembly to amyloid core sequences, challenging the importance of aromatic interactions in amyloidosis Proceedings of the National Academy of Sciences of the United States of America, January 16, 2013 Review Article
18 Exploring the amyloid proteome in immunoglobulin-derived lymph node amyloidosis using laser microdissection/tandem mass spectrometry American Journal of Hematology, April 25, 2013
19 Brain amyloid-β oligomers in ageing and Alzheimers disease Brain, April 16, 2013 Review Article
20 Mechanisms of action of naturally occurring antibodies against beta-amyloid on microglia Journal of Neuroinflammation, January 21, 2013 Review Article
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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