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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (32) Full Text Articles (287) Focus on Osteoarthritis161 The clinical utility and prognostic value of multiparameter flow cytometry immunophenotyping in AL amyloidosis Full Text Blood, February 2, 2012 Original Publication Date: February 1, 2011
162 Sternoclavicular Joint Infection: A Comparison of Two Surgical Approaches Full Text Annals of Thoracic Surgery, January 15, 2012 Original Publication Date: January 14, 2011
163 Cervical arthropathy caused by gout: stabilisation without decompression Full Text European Spine Journal, December 27, 2011 Original Publication Date: October 27, 2010
164 Can the Change in Center-edge Angle During Pincer Trimming Be Reliably Predicted Full Text Clinical Orthopedics and Related Research, December 26, 2011 Original Publication Date: October 25, 2010
165 Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis Full Text JAMA, December 24, 2011 Original Publication Date: June 23, 2011 Clinical Article
166 Diagnosing Periprosthetic Infection: False-positive Intraoperative Gram Stains Full Text Clinical Orthopedics and Related Research, December 21, 2011 Original Publication Date: October 21, 2010
167 The comparative safety of analgesics in older adults with arthritis Full Text Archives of Internal Medicine, December 16, 2011 Original Publication Date: December 15, 2010 Clinical Article
168 A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Maori, case and control sample sets Full Text Human Molecular Genetics, December 4, 2011 Original Publication Date: December 3, 2010
169 Rapid Correction of Bone Mass after Parathyroidectomy in an Adolescent with Primary Hyperparathyroidism Full Text Journal of Clinical Endocrinology and Metabolism, December 3, 2011 Original Publication Date: December 3, 2010
170 Alendronate for the Treatment of Pediatric Osteogenesis Imperfecta: A Randomized Placebo-Controlled Study Full Text Journal of Clinical Endocrinology and Metabolism, December 2, 2011 Original Publication Date: December 2, 2010
171 Association of BMD and FRAX Score With Risk of Fracture in Older Adults With Type 2 Diabetes Full Text JAMA, December 2, 2011 Original Publication Date: June 1, 2011
172 Autoimmune disease and subsequent risk of developing alimentary tract cancers among 4.5 million US male veterans Full Text Cancer, November 5, 2011 Original Publication Date: November 4, 2010
173 Fatty acid consumption and risk of fracture in the Women's Health Initiative Full Text American Journal of Clinical Nutrition, November 5, 2011 Original Publication Date: November 5, 2010
174 Improving the Recognition and Diagnosis of Fibromyalgia Full Text Mayo Clinic Proceedings, November 3, 2011 Original Publication Date: May 2, 2011
175 The influence of socio-demographic characteristics on consultation for back pain—a review of the literature Full Text Family Practice, November 3, 2011 Original Publication Date: November 3, 2010
176 Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues; in vitro and ex vivo studies in humans Full Text Diabetes Care, October 19, 2011 Original Publication Date: October 18, 2010
177 Long-term effects of anastrozole on bone mineral density: 7-year results from the ATAC trial Full Text Annals of Oncology, October 12, 2011 Original Publication Date: October 11, 2010 Clinical Article
178 Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis Full Text Proceedings of the National Academy of Sciences of the United States of America, September 30, 2011 Original Publication Date: March 30, 2011
179 Rheumatoid Arthritis-Interstitial Lung Disease-Associated Mortality Full Text American Journal of Respiratory and Critical Care Medicine, September 21, 2011 Original Publication Date: September 20, 2010
180 Osteoclast Activity and Subtypes as a Function of Physiology and Pathology—Implications for Future Treatments of Osteoporosis Full Text Endocrine Reviews, September 21, 2011 Original Publication Date: September 21, 2010
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013 Free full text
6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013
7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013
8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline
9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013
11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013
12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013 Free full text
13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013 Evidence Based Medicine
14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013
16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013
19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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