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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (24) Full Text Articles (287) Focus on Rheumatoid Arthritis101 Gradual strenuous running regimen predisposes to osteoarthritis due to cartilage cell death and altered levels of glycosaminoglycans Osteoarthritis and Cartilage , May 21, 2013 Review Article
102 Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes Osteoarthritis and Cartilage , May 21, 2013 Review Article
103 Characterisation of hand small joints arthropathy using high-resolution MRI--Limited discrimination between osteoarthritis and psoriatic arthritis European Radiology, May 21, 2013 Clinical Article
104 Symptomatic intracranial hypertension and prolonged hypocalcemia following treatment of Paget’s disease of the skull with zoledronic acid Journal of Bone and Mineral Metabolism, May 21, 2013 Clinical Article
105 Dynamic change and influence of osteoporotic back pain with vertebral fracture on related activities and social participation: evaluating reliability and validity of a newly developed outcome measure Journal of Bone and Mineral Metabolism, May 21, 2013 Clinical Article
106 Influence of education, marital status, occupation, and the place of living on skeletal status, fracture prevalence, and the course and effectiveness of osteoporotic therapy in women in the RAC-OST-POL Study Journal of Bone and Mineral Metabolism, May 21, 2013 Review Article
107 Anti-cyclic citrullinated peptide (anti-CCP) antibodies with brucellosis Rheumatology International, May 21, 2013 Review Article
108 Capnocytophaga spp. involvement in bone infections: a review International Journal of Antimicrobial Agents, May 21, 2013 Review Article
109 Behcet Disease-associated Uveitis Successfully Treated with Golimumab Ocular Immunology and Inflammation, May 21, 2013 Clinical Article
110 Current Perspectives on Ophthalmic Manifestations of Childhood Rheumatic Diseases Current Rheumatology Reports, May 21, 2013 Clinical Article
111 Osteoarthritis Progression Halted in Mice Full Text Johns Hopkins Medicine, May 21, 2013
112 Degenerative Changes Identified in Spinal Discs and Reversed With Drug Cocktail In Diabetic Mice The Mount Sinai Hospital, May 21, 2013
113 Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis Clinical and Experimental Rheumatology Online, May 20, 2013 Evidence Based Medicine Review Article Clinical Article
114 Validation of methotrexate-first strategy in early poor prognosis rheumatoid arthritis: Results from a randomized, double-blind, 2-year trial Arthritis & Rheumatism, May 20, 2013 Clinical Article
115 Diabetes and gout: efficacy and safety of febuxostat and allopurinol Diabetes, Obesity and Metabolism, May 20, 2013 Clinical Article
116 Treatment of ankylosing spondylitis with TNF blockers: a meta-analysis Rheumatology International, May 20, 2013 Evidence Based Medicine Review Article Clinical Article
117 The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and SLE Scandinavian Journal of Immunology, May 20, 2013 Clinical Article
118 Sonographic joint assessment in rheumatoid arthritis: Associations with clinical joint assessment in remission Arthritis & Rheumatism, May 20, 2013 Clinical Article
119 Clinical Features and Outcomes of Posterior Reversible Encephalopathy Syndrome in Patients with Systemic Lupus Erythematosus Arthritis Care & Research , May 20, 2013 Clinical Article
120 Predictors of self-reported health-related quality of life in systemic lupus erythematosus Rheumatology, May 20, 2013 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013 Free full text
6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013
7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013
8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline
9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013
11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013
12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013 Free full text
13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013 Evidence Based Medicine
14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013
16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013
19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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