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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (24) Full Text Articles (287) Focus on Rheumatoid Arthritis101 Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia Full Text Arthritis Research & Therapy, August 8, 2012
102 A randomized controlled trial of qigong for fibromyalgia Full Text Arthritis Research & Therapy, August 7, 2012 Clinical Article
103 Percutaneous vertebroplasty versus balloon kyphoplasty for treatment of osteoporotic vertebral compression fracture: a meta-analysis of randomised and non-randomised controlled trials Full Text International Orthopaedics, August 7, 2012 Original Publication Date: June 7, 2011 Evidence Based Medicine
104 Localized gastric amyloidosis differentiated histologically from scirrhous gastric cancer using endoscopic mucosal resection: a case report Full Text Journal of Medical Case Reports, August 7, 2012
105 IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1beta mediated degradation of nucleus pulposus in vitro Full Text Arthritis Research & Therapy, August 7, 2012
106 Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway Full Text Arthritis Research & Therapy, August 2, 2012
107 Immunoglobulin class switch recombination deficiencies Full Text Arthritis Research & Therapy, August 2, 2012
108 Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced arthritis Full Text Arthritis Research & Therapy, August 1, 2012
109 Monocyte populations as markers of response to adalimumab plus MTX in rheumatoid arthritis Full Text Arthritis Research & Therapy, July 31, 2012 Clinical Article
110 Superior semicircular canal dehiscence in East Asian women with osteoporosis Full Text BMC Ear, Nose and Throat Disorders, July 31, 2012
111 Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells Full Text Arthritis Research & Therapy, July 31, 2012
112 Carbonic anhydrase I is involved in the process of bone formation and is susceptible to ankylosing spondylitis Full Text Arthritis Research & Therapy, July 31, 2012
113 Autoantibody profiling to follow evolution of lupus syndromes Full Text Arthritis Research & Therapy, July 30, 2012
114 The effect of smoking or alcohol consumption on markers of systemic inflammation, immunoglobulin levels and immune response following pneumococcal vaccination in patients with arthritis Full Text Arthritis Research & Therapy, July 30, 2012
115 The optimized acupuncture treatment for neck pain caused by cervical spondylosis: a study protocol of a multicentre randomized controlled trial Full Text Trials, July 30, 2012
116 Association of estrogen receptor alpha gene polymorphisms with bone mineral density: a meta-analysis Full Text Chinese Medical Journal, July 27, 2012
117 Anti-TNFalpha therapy transiently improves high density lipoprotein cholesterol levels and microvascular endothelial function in patients with rheumatoid arthritis: a Pilot Study Full Text BMC Musculoskeletal Disorders, July 26, 2012 Clinical Article
118 Patients' hopes and expectations of a specialist chronic fatigue syndrome/ME service: a qualitative study Full Text Family Practice, July 26, 2012 Original Publication Date: July 26, 2011
119 A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: a randomised controlled trial protocol Full Text BMC Musculoskeletal Disorders, July 26, 2012
120 Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid Full Text BMC Musculoskeletal Disorders, July 26, 2012
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013 Free full text
6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013
7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013
8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline
9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013
11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013
12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013 Free full text
13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013 Evidence Based Medicine
14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013
16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013
19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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