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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (20) Full Text Articles (287) Focus on Fibromyalgia81 Serum Amyloid A Circulating Levels and Disease Activity in Patients with Juvenile Idiopathic Arthritis Full Text Yonsei Medical Journal, August 22, 2012
82 Regression of syndesmophyte after bone marrow transplantation for acute myeloid leukemia in a patient with ankylosing spondylitis: a case report Full Text Journal of Medical Case Reports, August 22, 2012
83 Anemia and the onset of gout in a population-based cohort of adults: Atherosclerosis Risk in Communities study Full Text Arthritis Research & Therapy, August 21, 2012 Clinical Article
84 Early menopause and severity of rheumatoid arthritis in women over 45 years of age Full Text Arthritis Research & Therapy, August 21, 2012
85 Early systemic sclerosis: short-term disease evolution and factors predicting the development of new manifestations of organ involvement Full Text Arthritis Research & Therapy, August 20, 2012 Clinical Article
86 Atorvastatin inhibit osteoclastogenesis by decreasing the expression of RANKL in the synoviocytes of rheumatoid arthritis Full Text Arthritis Research & Therapy, August 20, 2012 Clinical Article
87 Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes Full Text BMC Musculoskeletal Disorders, August 20, 2012
88 Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time Full Text Clinical Interventions in Aging, August 20, 2012
89 Activity of the neuroendocrine axes in patients with polymyalgia rheumatica before and after TNF-alpha blocking etanercept treatment Full Text Arthritis Research & Therapy, August 17, 2012 Clinical Article
90 Factor H autoantibodies and deletion of complement factor H-related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome Full Text Arthritis Research & Therapy, August 17, 2012
91 Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations Full Text Arthritis Research & Therapy, August 16, 2012
92 Glucocorticoid receptor gene polymorphisms and disease activity during pregnancy and the postpartum period in rheumatoid arthritis Full Text Arthritis Research & Therapy, August 15, 2012
93 The impact of tocilizumab on physical function and quality of life in patients with rheumatoid arthritis: a systematic literature review and interpretation Full Text Open Access Rheumatology: Research and Reviews, August 14, 2012 Evidence Based Medicine Clinical Article
94 Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms Full Text Archives of Internal Medicine, August 10, 2012 Original Publication Date: August 9, 2011 Clinical Article
95 Platelet rich plasma therapy: future or trend Full Text Arthritis Research & Therapy, August 10, 2012
96 Methylene Blue in the Treatment of Discogenic Low Back Pain Full Text Pain Physician, August 9, 2012 Clinical Article
97 Inflammation associated anemia and ferritin as disease markers in systemic lupus erythematosus Full Text Arthritis Research & Therapy, August 9, 2012 Clinical Article
98 Gender and the treatment of immune-mediated chronic inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease and psoriasis: an observational study Full Text BMC Medicine, August 9, 2012
99 Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA Full Text Arthritis Research & Therapy, August 9, 2012
100 Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial Full Text Trials, August 8, 2012 Clinical Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 New biologic therapy for systemic lupus erythematosus Current Opinion in Pharmacology , May 10, 2013
2 Intra-articular glucocorticoids for acute gout Cochrane Reviews, May 3, 2013
3 Vitamin D and systemic lupus erythematosus: an update Expert Review of Clinical Immunology, May 9, 2013 Review Article
4
Use of Lipid-lowering Agents in Rheumatoid Arthritis: A Population-based Cohort Study
The Journal of Rheumatology, May 2, 2013
Exclusive Author Commentary
5 Treatment of acute septic arthritis The Pediatric Infectious Disease Journal, May 24, 2013 Review Article
6 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013
7 Use of New Oral Anticoagulants in Antiphospholipid Syndrome Current Rheumatology Reports, May 7, 2013
8 The effect of two golimumab doses on radiographic progression in ankylosing spondylitis: results through 4 years of the GO-RAISE trial Annals of Rheumatic Diseases, May 7, 2013
9 Dextrose prolotherapy for knee osteoarthritis: A randomized controlled trial Annals of Family Medicine, May 21, 2013 Free full text
10 Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis Clinical and Experimental Rheumatology Online, May 20, 2013 Evidence Based Medicine Review Article
11 The role of vitamin D supplementation in patients with rheumatic diseases Nature Reviews Rheumatology , May 15, 2013 Clinical Guideline
12 Steroid injection for inferior heel pain: a randomised controlled trial Annals of Rheumatic Diseases, May 21, 2013
13 Vaccination and Inflammatory Arthritis: Overview of Current Vaccines and Recommended Uses in Rheumatology Current Rheumatology Reports, May 2, 2013
14 Monotherapy with tocilizumab or TNF-alpha inhibitors in patients with rheumatoid arthritis: efficacy, treatment satisfaction, and persistence in routine clinical practice Clinical Rheumatology, May 24, 2013
15 Clinical features distinguishing lymphoma development in primary Sjogrens syndrome--A retrospective cohort study Seminars in Arthritis and Rheumatism, May 10, 2013
16 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
17 Punctal plugs versus artificial tears for treating primary Sjogrens syndrome with keratoconjunctivitis SICCA: a comparative observation of their effects on visual function Rheumatology International, May 7, 2013
18 Clinical Course, Prognosis, and Causes of Death in Mixed Connective Tissue Disease The Journal of Rheumatology, May 2, 2013
19 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
20 Comparing the effects of individualized, standard, sham and no acupuncture in the treatment of knee osteoarthritis: a multicenter randomized controlled trial Trials, May 10, 2013 Free full text
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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