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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
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Articles
Latest (24) Full Text Articles (287) Focus on Osteoporosis41 A case of isolated aorta occlusion caused by takayasu arteritis JCR: Journal of Clinical Rheumatology, May 23, 2013
42 A case of bilateral hemarthrosis due to pseudoaneurysms in a patient on anticoagulation therapy JCR: Journal of Clinical Rheumatology, May 23, 2013
43 Granulomatosis with polyangiitis presenting as henoch-schonlein purpura in children JCR: Journal of Clinical Rheumatology, May 23, 2013
44 Palmar fasciitis and polyarthritis syndrome in pancreatic carcinoma JCR: Journal of Clinical Rheumatology, May 23, 2013
45 Insufficient deep-colored vegetable intake is associated with higher fragility fracture rate in postmenopausal Taiwanese women Full Text International Journal of Gerontology, May 23, 2013 Review Article
46 Steroid injection for inferior heel pain: a randomised controlled trial Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
47 Comparative efficacy of pharmacological and non-pharmacological interventions in fibromyalgia syndrome: network meta-analysis Annals of Rheumatic Diseases, May 22, 2013 Evidence Based Medicine Review Article Clinical Article
48 Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
49 Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study) Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
50 Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
51 A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
52 Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
53 Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
54 Efficacy of rituximab in systemic manifestations of primary Sjogrens syndrome: results in 78 patients of the AutoImmune and Rituximab registry Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
55 Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
56 Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK) Annals of Rheumatic Diseases, May 22, 2013 Clinical Article
57 Analysis of knee flexion characteristics and how they alter with the onset of knee osteoarthritis: a case control study Full Text BMC Musculoskeletal Disorders, May 22, 2013 Evidence Based Medicine Clinical Article
58 MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes Annals of Rheumatic Diseases, May 22, 2013 Review Article
59 Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment Annals of Rheumatic Diseases, May 22, 2013 Review Article
60 Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis Annals of Rheumatic Diseases, May 22, 2013 Review Article
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013 Free full text
6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013
7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013
8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline
9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013
11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013
12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013 Free full text
13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013 Evidence Based Medicine
14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013
16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013
19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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