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Rheumatology News & Articles
What you'll find here at MDLinx Rheumatology: The top rheumatology clinical articles of the day, plus MDLinx exclusive content
- Our medical editors bring you the best key learnings published in the top peer-reviewed rheumatology medical journals. You'll find overviews here ranked and organized by topic on rheumatoid arthritis, joint and back pain, osteoarthritis, lupus and autoimmune diseases, osteoporosis and bone fractures. In a matter of minutes, you and all the members of your patient care team can stay current on the literature as it is published.
- MDLinx exclusive content includes monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD, as well as clinical pearls from The Smartest Internist, The Smartest Family Physician, and The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Rheumatology
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Articles
Latest (35) Full Text Articles (287) Focus on Osteoarthritis281 Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply Annals of Rheumatic Diseases, May 7, 2013 Review Article
282 Deletion of the receptor tyrosine kinase Tyro3 inhibits synovial hyperplasia and bone damage in arthritis Annals of Rheumatic Diseases, May 7, 2013 Review Article
283 Proteomic analyses and identification of arginine methylated proteins differentially recognized by autosera from anti-Sm positive SLE patients Full Text Journal of Biomedical Science, May 7, 2013
284 Intra-articular glucocorticoids for acute gout Cochrane Reviews, May 6, 2013 Clinical Article
285 MRI-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: Data from the Osteoarthritis Initiative Arthritis & Rheumatism, May 6, 2013 Clinical Article
286 Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study Modern Rheumatology, May 6, 2013 Clinical Article
287 Atherosclerosis and cardiovascular disease in the spondyloarthritides, particularly ankylosing spondylitis and psoriatic arthritis Clinical and Experimental Rheumatology Online, May 6, 2013 Clinical Article
288 Effect of gender on clinical presentation in systemic lupus erythematosus Rheumatology, May 6, 2013 Clinical Article
289 Association of the sense of coherence with physical and psychosocial health in the rehabilitation of osteoarthritis of the hip and knee: a prospective cohort study Full Text BMC Musculoskeletal Disorders, May 6, 2013 Clinical Article
290 Interventions in Pediatric Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Systematic Review Journal of Adolescent Health, May 6, 2013 Evidence Based Medicine
291 Soluble Biomarkers Associated with Response to Treatment with Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis The Journal of Rheumatology, May 6, 2013 Clinical Article
292 Survival and Causes of Death in an Unselected and Complete Cohort of Norwegian Patients with Systemic Sclerosis The Journal of Rheumatology, May 6, 2013 Review Article
293 Interaction of HLA-DRB1*09:01 and *04:05 with Smoking Suggests Distinctive Mechanisms of Rheumatoid Arthritis Susceptibility Beyond the Shared Epitope The Journal of Rheumatology, May 6, 2013 Clinical Article
294 Lymphopaenia, Anti-Ro/Anti-RNP Autoantibodies, Renal Involvement and Cyclophosphamide Use Correlate with Increased Risk of Herpes Zoster in Patients with Systemic Lupus Erythematosus Acta Dermato-Venereologica, May 6, 2013 Clinical Article
295 Classification and Diagnostic Investigation in Inflammatory Myopathies: A Study of 99 Patients The Journal of Rheumatology, May 6, 2013 Clinical Article
296 Variable Association of Reactive Intermediate Genes with Systemic Lupus Erythematosus in Populations with Different African Ancestry The Journal of Rheumatology, May 6, 2013 Review Article
297 Reconstruction of Bone Defects After Osteomyelitis with Nonvascularized Fibular Graft A Retrospective Study in Twenty-six Children The Journal of Bone & Joint Surgery, May 6, 2013 Evidence Based Medicine
298 Prevention of steroid-induced low bone mineral density in children with renal diseases: a systematic review Nephrology Dialysis Transplantation, May 6, 2013 Evidence Based Medicine Review Article Clinical Article
299 Limb girdle muscular dystrophy type 2B masquerading as inflammatory myopathy: case report Pediatric Rheumatology, May 6, 2013
300 Recurrent Compartment Syndrome in a Patient With Clinical Features of a Connective Tissue Disorder American Journal of Medical Genetics Part A, May 6, 2013
Clinical Pearls in Rheumatology
- Independent predictors of disease activity in patients with systemic lupus include age, renal activity, immunosuppressant use and pre-existing organ damage
- When treating rheumatoid arthritis (RA), male sex, short duration of symptoms and less tender joints at baseline were found to be independent predictors of sustained remission with conventional DMARDs
- Higher baseline DAS28 scores and positive rheumatoid factor status are significantly associated with an improvement in response to rituximab treatment
Highlights in Rheumatology
ACPA correlate with disease progression in JIA
In a study involving 74 patients with juvenile idiopathic arthritis (JIA), 26 patients had detectable anti-citrullinated protein antibodies (ACPA). The ACPA titers correlated with disease progression at baseline and after a median follow-up of 11.5 months. In addition to predicting disease severity and progression, the authors concluded that ACPA were superior to IgM-RF in diagnosing JIA.
Read the article summaryPredicting cardiovascular mortality in SLE
In a study involving 208 patients with SLE followed for 12 years, 42 deaths occurred, 48% of which were considered to be cardiovascular mortalities. Age, increased cystatin C levels, and arterial disease were predictive of all-cause mortality. Cigarette smoking and increased sVCAM-1, hsCRP, abeta2GP1, and aPL antibody levels were predictive of cardiovascular mortality.
Read the article summaryAnti-apoA-1 antibodies predict cardiovascular disease in RA patients
In a study conducted at the University of Geneva involving 118 patients with rheumatoid arthritis, but without cardiovascular disease at baseline, the 10-year Framingham cardiovascular risk score (FRS) was improved with the inclusion of the anti-apoA-1 antibody titer. The median follow-up was 9 years and the incidence of cardiovascular disease was 16%. Other biomarkers, including the NT-proBNP, oxLDL, CRP, and RF levels and the anti-citrullinated peptide antibody titer, did not improve the FRS.
Read the article summaryMost Popular Rheumatology Articles
Last month's top read Top Articles of 20121 Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) Current Medical Research and Opinion, April 3, 2013
2 Antibiotics for Treatment of Reactive Arthritis: A Systematic Review and Metaanalysis The Journal of Rheumatology, April 18, 2013 Evidence Based Medicine Review Article
3 EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Annals of Rheumatic Diseases, April 10, 2013
4 Targeted therapies for systemic sclerosis Nature Reviews Rheumatology , April 10, 2013
5 Complementary and alternative exercise for fibromyalgia: a meta-analysis Journal of Pain Research, April 2, 2013 Free full text
6 Late-onset systemic lupus erythematosus: clinical features, course, and prognosis Clinical Rheumatology, March 26, 2013
7 Statin Use in Giant Cell Arteritis: A Retrospective Study The Journal of Rheumatology, April 3, 2013
8 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline
9 Safety of Abatacept Administered Intravenously in Treatment of Rheumatoid Arthritis: Integrated Analyses of up to 8 Years of Treatment from the Abatacept Clinical Trial Program The Journal of Rheumatology, April 16, 2013
10 New therapeutics in systemic lupus erythematosus Current Opinion in Rheumatology, April 1, 2013
11 New treatments for osteoarthritis Current Opinion in Rheumatology, March 29, 2013
12 The association of gout with sleep disorders: a cross-sectional study in primary care BMC Musculoskeletal Disorders, April 5, 2013 Free full text
13 Intra-articular corticosteroid injection in osteoarthritis of the knee and hip: Factors predicting pain relief--A systematic review Seminars in Arthritis and Rheumatism, February 4, 2013 Evidence Based Medicine
14 Novel aspects of Sjogren's syndrome in 2012 BMC Medicine, April 16, 2013 Free full text
15 Creatine supplementation in fibromyalgia: A double-blind, randomized, placebo-controlled trial Arthritis Care & Research , April 3, 2013
16 Current diagnostic tools for Sjogrens syndrome International Journal of Clinical Rheumatology, April 3, 2013
17 A meta-analysis of healing and prevention of digital ulcers (DU) in systemic sclerosis (SSc) Arthritis Care & Research , April 2, 2013 Evidence Based Medicine
18 The Early Protective Effect of Hydroxychloroquine on the Risk of Cumulative Damage in Patients with Systemic Lupus Erythematosus The Journal of Rheumatology, April 18, 2013
19 The impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis (RA) vs. non-RA subjects: Results from a population-based study Arthritis Care & Research , April 17, 2013
20 Safety of Rituximab in Combination with Other Biologic Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis: An Open-label Study The Journal of Rheumatology, April 2, 2013
Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatology more
Other Topics in Rheumatology
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