Low vitamin D associated with statin-induced myalgia
As reported in Clinical Therapeutics, of 450 patients prescribed high-dose simvastatin (80 mg qd) for dyslipidemia, 11.1% complained of myalgias. The vitamin D level was lower in patients with myalgias than patients without myalgias (26.2 vs. 36.3 ng/mL).
Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients
As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).
Serum uric acid correlates with erectile dysfunction
As reported in the Journal of Sexual Medicine, men with erectile dysfunction have higher levels of serum uric acid than men without (6.12 mg/dL vs. 4.97 mg/dL). Comparing the highest and lowest tertiles for serum uric acid, the OR for erectile dysfunction was 5.95.