1One year in review: Novelties in the treatment of rheumatoid arthritisClinical and Experimental Rheumatology Online  Review Article
2Outcomes associated with early post-traumatic osteoarthritis and other negative health consequences 3-10 years following knee joint injury in youth sportOsteoarthritis and Cartilage  Clinical Article
3Reactive arthritis – Overview and update with clinical casesAktuelle Rheumatologie  Clinical Article
4Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patientsJournal of Immunological Methods  Clinical Article
5Intra-individual assessment of inflammatory severity and cartilage composition of finger joints in rheumatoid arthritisSkeletal Radiology  Clinical Article
6Safety of biologics in rheumatoid arthritis: Data from randomized controlled trials and registriesBiologics: targets & therapy  Full Text  Review Article
7Adult primary central nervous system vasculitis treatment and course: Analysis of 163 patientsArthritis & Rheumatism  Clinical Article
8Cross-sectional neurocognitive data do not support a transition from fibrofog to Alzheimer’s disease in fibromyalgia patientsJCR: Journal of Clinical Rheumatology  Clinical Article
9Cognitive performance scores for the pediatric automated neuropsychological assessment metrics in childhood-onset systemic lupus erythematosusArthritis Care & Research  Clinical Article
10Anakinra for the treatment of acute severe gout in critically ill patientsSeminars in Arthritis and Rheumatism  Clinical Article
1Prescription opioid analgesic use among adults: United States, 1999–2012U.S. National Center for Health Statistics News
2Antifreeze protein from ticks fights frostbite in miceYale School of Medicine News
3Million man study examines long-term effects of blocking inflammationUniversity of Cambridge News
4Rheumatology Research Foundation shares excitement about specialty with medical students, residentsThe Rheumatologist
5Painkillers for chronic pain prescribed in higher doses and continued over longer periods raise drug overdose riskUniversity of Texas Health Science Center at San Antonio News
6The ACR/ARHP Annual Meeting: Lung fibrosisThe Rheumatologist
7The ACR/ARHP Annual Meeting: Biomarker developmentThe Rheumatologist
8The ACR/ARHP Annual Meeting: Psoriatic arthritisThe Rheumatologist
9The ACR/ARHP Annual Meeting: Diagnosing PACNS and its mimicsThe Rheumatologist
10The ACR/ARHP Annual Meeting: Lupus nephritisThe Rheumatologist

Show Me:

Low vitamin D associated with statin-induced myalgia

As reported in Clinical Therapeutics, of 450 patients prescribed high-dose simvastatin (80 mg qd) for dyslipidemia, 11.1% complained of myalgias. The vitamin D level was lower in patients with myalgias than patients without myalgias (26.2 vs. 36.3 ng/mL).

Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients

As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).

Serum uric acid correlates with erectile dysfunction

As reported in the Journal of Sexual Medicine, men with erectile dysfunction have higher levels of serum uric acid than men without (6.12 mg/dL vs. 4.97 mg/dL). Comparing the highest and lowest tertiles for serum uric acid, the OR for erectile dysfunction was 5.95.

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Clinical Pearls

Clinical Pearl from Smartest DocThe guidelines established by the International Society of Nephrology/Renal Pathology Society 2003 classification of Lupus Nephritis are recommended for use by the acronym 2012 Guidelines for the Management, Screening, and Classification of Lupus Nephritis.

Clinical Pearl from Smartest DocRapid loss of bone mineral density emphasizes the need for osteoporosis prevention in the post transplantation period.

Clinical Pearl from Smartest DocLupus erythematosus can be induced through known pharmacologic interactions.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List