We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain: a systematic reviewPain Physician, May 22, 2015  Full Text  Evidence Based Medicine  Review Article
2Effectiveness of parasagittal interlaminar epidural local anesthetic with or without steroid in chronic lumbosacral pain: a randomized, double-blind clinical trialPain Physician, May 22, 2015  Full Text  Clinical Article
3Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization painPain Physician, May 22, 2015  Full Text  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Agriculture, declining mobility drove humans' shift to lighter bonesJohns Hopkins Medicine, May 20, 2015
2First patient-led research registry for arthritis patients launchedUAB Medicine, May 20, 2015
3Physical therapy, exercise advances for knee osteoarthritisThe Rheumatologist, May 20, 2015
4Include men in osteoporosis screening guidelinesNational Jewish Health, May 19, 2015
5Soft-tissue engineering for hard-working cartilageTechnische Universität München, May 18, 2015
6Breakthrough opens door to safer lupus drugsMonash University News, May 15, 2015
7Yale researchers solve multiple sclerosis puzzleYale School of Medicine News, May 14, 2015
8Protein identified that serves as a "brake" on inflammationSt. Jude Children's Research Hospital News, May 12, 2015

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Serum uric acid correlates with erectile dysfunction

As reported in the Journal of Sexual Medicine, men with erectile dysfunction have higher levels of serum uric acid than men without (6.12 mg/dL vs. 4.97 mg/dL). Comparing the highest and lowest tertiles for serum uric acid, the OR for erectile dysfunction was 5.95.

Sclerostin associated with bone turnover in elderly women

As reported in the Journal of American Geriatrics Society, sclerostin levels are associated with osteocalcin, C-termial telopeptide of type I collagen, and PTH levels in elderly women (≥ 70 y) in nursing homes, but not mortality.

FCGR3B loss increases susceptibility to SLE and LN

As reported in the International Journal of Rheumatic Diseases, a meta-analysis of 6 studies has shown that a loss of FCGR3B copy number is associated with increased susceptibility to SLE (OR=1.77) and lupus nephritis (OR=2.02).

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Clinical Pearls

Clinical Pearl from Smartest DocMarkers useful inidentifying candidates for tocilizumab discontinuation include serum interleukin-6 (IL-6) and matrix metalloproteinase-3 (MMP-3).

Clinical Pearl from Smartest DocGood control of plasma homocysteine may prevent or delay some of the complications of homocystinuria.

Clinical Pearl from Smartest DocRenal involvement is main cause of mortality and morbidity in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

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