The Latest Journal Articles in Rheumatology

1EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practiceAnnals of Rheumatic Diseases, April 17, 2015  Review Article
2Risk of venous thromboembolism after total knee arthroplasty in patients with rheumatoid arthritisThe Journal of Rheumatology, April 17, 2015  Clinical Article
3The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritisAnnals of Rheumatic Diseases, April 17, 2015  Clinical Article
4Cardiac troponin testing in idiopathic inflammatory myopathies and systemic sclerosis-spectrum disorders: Biomarkers to distinguish between primary cardiac involvement and low-grade skeletal muscle disease activityAnnals of Rheumatic Diseases, April 17, 2015  Clinical Article
5Disease relapses among patients with giant cell arteritis: A prospective, longitudinal cohort studyThe Journal of Rheumatology, April 17, 2015  Clinical Article
6Disease severity and pregnancy outcomes in women with rheumatoid arthritis: Results from the Organization of Teratology Information Specialists Autoimmune Diseases in Pregnancy ProjectThe Journal of Rheumatology, April 17, 2015  Clinical Article
7Fetal microchimerism in kidney biopsies of lupus nephritis patients may be associated with a beneficial effectArthritis Research & Therapy, April 17, 2015  Clinical Article
8Randomized trial of the effectiveness of a non-pharmacological multidisciplinary face-to-face treatment program on daily function compared to a telephone-based treatment program in patients with generalized osteoarthritisOsteoarthritis and Cartilage , April 17, 2015  Clinical Article
9Dissecting the heterogeneity of macrophage activation syndrome complicating systemic juvenile idiopathic arthritisThe Journal of Rheumatology, April 17, 2015  Clinical Article
10May neutrophil-lymphocyte and platelet-lymphocyte ratios indicate disease activity in ankylosing spondylitis?Archives of Rheumatology, April 17, 2015  Full Text  Clinical Article
1Your pain reliever may also be diminishing your joyOhio State University News, April 16, 2015
2WHO calls for increased transparency in medical researchWHO - World Health Organization, April 15, 2015
3How bones reflect genetic variation among populationsGarvan Institute of Medical Research News, April 14, 2015
4First look at 'wasabi receptor' brings insights for pain drug developmentUCSF News, April 13, 2015
5Research goal: Catch the interferons that cause lupus, one cell at a timeUAB Medicine, April 13, 2015
6UAB researcher probes role of a master gene in skeletal formationUAB Medicine, April 13, 2015
7Depression often co-occurs with joint diseasesUniversity of Basel News, April 09, 2015
8Study identifies protein that triggers lupus-associated immune system activationMassachusetts General Hospital, April 08, 2015

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Increased prevalence of osteoporosis in morbidly obese

As reported in the International Journal of Clinical Practice, while there is a decreased prevalence of osteoporosis up to a BMI of 40 kg/m2, the prevalence of osteoporosis increases in patients with a BMI > 40 kg/m2, which is thought to be due to decreased weight-bearing exercise.

Sclerostin associated with bone turnover in elderly women

As reported in the Journal of American Geriatrics Society, sclerostin levels are associated with osteocalcin, C-termial telopeptide of type I collagen, and PTH levels in elderly women (≥ 70 y) in nursing homes, but not mortality.

Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients

As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).

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Clinical Pearls

Clinical Pearl from Smartest DocApparent diffusion coefficient is a parameter for detection of vertebral bone marrow infiltration in children with Gaucher's disease type I and III.

Clinical Pearl from Smartest DocPatients with a 20% or greater chance of experiencing an osteoporotic fracture within 10 years should receive osteoporosis therapy.

Clinical Pearl from Smartest DocThe American College of Rheumatology provides treatment recommendations for Class IV/V lupus nephritis in the presence of cellular crescents.

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