Enhanced immunoprotective effects by Anti-IL17 antibody translates to improved skeletal parameters under estrogen deficiency compared to Anti-RANKL and Anti-TNFα antibodies
Journal of Bone and Mineral Research,  Clinical Article

Tyagi AM, et al. – Activated T cell has a key role in the interaction between bone and immune system. T cells produce pro–inflammatory cytokines including, RANKL, TNF–α and IL–17, all of which augment osteoclastogenesis. Based on the superior immunoprotective effects of anti–IL17 which appears to translate to a better skeletal preservation, the authors propose beginning clinical trials using a humanized antibody against IL–17 for treatment of post–menopausal osteoporosis.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Rheumatology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Rheumatology Articles

Indexed Journals in Rheumatology: Arthritis & Rheumatism, Annals of Rheumatic Diseases, Journal of Rheumatologymore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close