Does Periodontopathic Bacterial Infection Contribute to the Etiopathogenesis of the Autoimmune Disease Rheumatoid Arthritis? Full Text
Discovery Medicine, 05/31/2012
Ogrendik M – Antibodies to Gram–negative, anaerobic periodontal pathogens such as Porphyromonas gingivalis, Prevotella intermedia, Prevotella melaninogenica, and Tannerella forsythia have been detected in the serum and synovial fluid of rheumatoid arthritis (RA) patients. These pathogens have also been identified in the synovial fluid of RA patients, with higher levels of bacterial DNA in RA patients than in controls. This review examines the association between periodontopathic bacteria and the etiology of RA.