The classification for psoriatic arthritis (CASPAR) criteria -- A retrospective feasibility, sensitivity, and specificity study
The Journal of Rheumatology, 11/28/2011
– This study demonstrates that the feasibility, specificity, and sensitivity of the CASPAR are maintained when adapted for retrospective use to classify an established research cohort.
480 patient records were reviewed from the Royal National Hospital for Rheumatic Diseases Psoriatic Arthritis (PsA) cohort and for 100 consecutive controls with inflammatory arthritis from a general rheumatology clinic
The CASPAR score was modified for retrospective use; both “inflammation” and “current psoriasis” were recorded as present if they had ever been confirmed in the rheumatology clinic
Sensitivity and specificity of CASPAR criteria were compared with expert clinical diagnosis
480 database records were identified
9 sets of records had been lost or destroyed
Diagnoses had changed in 15 cases, which were transferred to the control arm, leaving 456 patients with an expert diagnosis of PsA
Of 115 controls, 96 had RA, 5 OA, 3 reactive arthritis, 3 seronegative arthritis, 3 undifferentiated arthralgia, 2 ankylosing spondylitis, 1 spondyloarthritis, and 2 systemic sclerosis
Sensitivity (99.7%) and specificity (99.1%) were both high and equivalent to previous reports
Sensitivity remained high even after inclusion of 7 PsA patients with insufficient data to complete the CASPAR assessment (sensitivity 98.2%, specificity 99.1%)
Criteria were found to be easy and practical to apply to case records
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