Low bone mineral density and fragility fractures in permanent vegetative state patients

Journal of Bone and Mineral Research, 10/29/2013

Disuse of the musculoskeletal system causes bone loss. Whether patients in vegetative state, a dramatic example of immobilization following severe brain injury, suffer from bone loss and fractures is currently unknown. High bone turnover and low bone mineral density is highly prevalent in vegetative state patients translating into a clinically relevant problem as shown by fragility fractures in 20% of patients over a time period of 5 years.

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