Efficacy of total joint arthroplasty in patients with established rheumatoid arthritis: Improved longitudinal effects on disease activity but not on health-related quality of life
Modern Rheumatology, 03/14/2011
Momohara S et al.
– This study aimed to assess changes in disease activity and health-related quality of life after TJA in patients with established RA.
Analyzed the effect of total knee arthroplasty (TKA) and total hip arthroplasty (THA) on RA disease activity in an observational cohort of RA patients
Of registered RA patients, 333 TKA and 77 THA patients followed for 5 years after surgery
RA disease activity and health-related quality of life measured using Disease Activity Score 28 (DAS28) and Japanese version of Stanford health assessment questionnaire (J-HAQ)
Mean DAS28 in TKA patients decreased from 4.66 (preoperatively) to 4.02 (3 years postoperatively) and to 3.94 (5 years postoperatively); mean DAS28 in THA patients decreased from 4.41 (preoperatively) to 3.99 (3 years postoperatively) and to 3.92 (5 years postoperatively)
Mean J-HAQ for TKA remained essentially unchanged, ranging from 1.48 (preoperatively) to 1.45 (3 years postoperatively) and to 1.47 (5 years postoperatively); mean J-HAQ for THA also remained unchanged, ranging from 1.74 (preoperatively) to 1.74 (3 years postoperatively) and to 1.73 (5 years postoperatively)
Of total J-HAQ score, lower limb score improved while upper limb score worsened
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