Using the same bone density reference database for men and women provides a simpler estimation of fracture risk

Journal of Bone and Mineral Research, 10/01/2010

Although low bone mineral density (BMD) predicts fractures, there are postulated sex differences in the fracture “threshold.” Some studies demonstrate a higher mean BMD for men with fractures than for women, whereas others note similar absolute risk at the same level of BMD. The authors conclude that no adjustment for sex is necessary when using common reference data for both men and women, whereas using sex-specific reference data requires a substantial secondary adjustment for sex.

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