Leptin and ghrelin in Korean systemic lupus erythematosus

Lupus, 01/26/2010

Kim HA et al. – Elevated serum leptin levels have been described in patients with systemic lupus erythematosus (SLE), however these studies have provided no information regarding the ghrelin levels. The findings of this study suggest that leptin and ghrelin play a role in clinical manifestations observed in SLE.

Methods

  • Clinical significance of serum leptin and ghrelin levels in SLE investigated

Results

  • Leptin levels of SLE patients higher than those of normal healthy controls, while the ghrelin levels of SLE were lower
  • Ghrelin levels significantly lower in SLE patients with arthritis and hematologic disorder

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