Exercise for fibromyalgia pain: A meta-analysis of randomized controlled trials
Current Rheumatology Reviews, 01/04/2010
Ramel J et al. – Physical exercise may have positive effects on pain reduction in patients with FM. Long-term, rigorous and well-controlled randomized trials are warranted.
Comprehensive search of 8 western databases and reference lists through March 2009
Included randomized controlled trials (RCTs) with pain as an endpoint, measured by the Fibromyalgia Impact Questionnaire (FIQ) or a visual analogue scale (VAS)
Exercise treatments were compared with no-exercise control group
Study quality assessed by Jadad scale
Calculated effect sizes to assess the magnitude of treatment effect, and meta-analyzed for overall effect
45 studies critically appraised for effects on pain
10 RCTs published between 1992 and 2008, conducted in Europe and North America met eligibility criteria with 767 participants (98% women)
Mean age was 47 years and mean symptom duration was 10 years
Meta-analysis results showed that 6 to 24 weeks of aerobic, strength training, pool and multi-component exercise had a statistically significant decrease in pain outcomes versus education, usual care and non-exercise controls
Pooled effect size was 0.45 (95% Confidence Interval, 0.09 to 0.80)
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