We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain: a systematic reviewPain Physician, May 22, 2015  Full Text  Evidence Based Medicine  Review Article
2Effectiveness of parasagittal interlaminar epidural local anesthetic with or without steroid in chronic lumbosacral pain: a randomized, double-blind clinical trialPain Physician, May 22, 2015  Full Text  Clinical Article
3Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization painPain Physician, May 22, 2015  Full Text  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Agriculture, declining mobility drove humans' shift to lighter bonesJohns Hopkins Medicine, May 20, 2015
2First patient-led research registry for arthritis patients launchedUAB Medicine, May 20, 2015
3Physical therapy, exercise advances for knee osteoarthritisThe Rheumatologist, May 20, 2015
4Include men in osteoporosis screening guidelinesNational Jewish Health, May 19, 2015
5Soft-tissue engineering for hard-working cartilageTechnische Universit√§t M√ľnchen, May 18, 2015
6Breakthrough opens door to safer lupus drugsMonash University News, May 15, 2015
7Yale researchers solve multiple sclerosis puzzleYale School of Medicine News, May 14, 2015
8Protein identified that serves as a "brake" on inflammationSt. Jude Children's Research Hospital News, May 12, 2015

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Increased prevalence of osteoporosis in morbidly obese

As reported in the International Journal of Clinical Practice, while there is a decreased prevalence of osteoporosis up to a BMI of 40 kg/m2, the prevalence of osteoporosis increases in patients with a BMI > 40 kg/m2, which is thought to be due to decreased weight-bearing exercise.

Serum uric acid correlates with erectile dysfunction

As reported in the Journal of Sexual Medicine, men with erectile dysfunction have higher levels of serum uric acid than men without (6.12 mg/dL vs. 4.97 mg/dL). Comparing the highest and lowest tertiles for serum uric acid, the OR for erectile dysfunction was 5.95.

Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients

As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).

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Clinical Pearls

Clinical Pearl from Smartest DocPharmacological treatments influence outpatient antimicrobial use in children with rheumatic diseases.

Clinical Pearl from Smartest DocExtended use of glucocorticoids increases risk for osteoporosis and osteoporotic fractures.

Clinical Pearl from Smartest DocMolecular players are linked in the pathogenesis of scleroderma.

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