We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Subclincal atherosclerosis in Behçet's disease: A systematic review & metanalysisSeminars in Arthritis and Rheumatism, July 07, 2015  Evidence Based Medicine  Review Article
2The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progressionAnnals of Rheumatic Diseases, July 07, 2015  Clinical Article
3Efficacy and safety of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional DMARDs in patients with RA at week 97 (SUMMACTA)Annals of Rheumatic Diseases, July 07, 2015  Clinical Article
4Atacicept combination with rituximab in rheumatoid arthritis: Randomised Atacicept for redUction of siGns and symptoms in rheUmatoid arthritiS TrialArthritis & Rheumatism, July 07, 2015  Clinical Article
5Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritisAnnals of Rheumatic Diseases, July 07, 2015  Clinical Article
6EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practiceAnnals of Rheumatic Diseases, July 07, 2015  Review Article
7Gene profiling reveals specific molecular pathways in the pathogenesis of atherosclerosis and cardiovascular disease in antiphospholipid syndrome, systemic lupus erythematosus and antiphospholipid syndrome with lupusAnnals of Rheumatic Diseases, July 07, 2015  Clinical Article
8Tubulointerstitial lesions in lupus nephritis: International multicenter study in a large cohort of patients with repeat biopsyNephrology, July 07, 2015  Clinical Article
9Validation of statistical shape modelling to predict hip osteoarthritis in females: Data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford)Rheumatology, July 07, 2015  Clinical Article
10A right ventricular diastolic impairment is common in systemic sclerosis and is associated with other target-organ damageSeminars in Arthritis and Rheumatism, July 07, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1New test could predict arthritis drug failure in patientsThe University of Manchester News, July 07, 2015
2Class of 2018 student's research appears in Arthritis and Rheumatology journalWayne State University School of Medicine News, July 06, 2015
3UCLA study reveals bone-building protein's impact on bone stem cellsUCLA Health System, July 02, 2015
4Scleroderma treatment breakthrough ID’d by BUSM researchersBoston University School of Medicine, June 26, 2015
5Apremilast in plaque psoriasis and psoriatic arthritis: No added benefit can be derivedGerman Institute for Quality and Efficiency in Health Care (IQWiG), June 26, 2015
6Cells too stiff to scavenge leads to lupus, an autoimmune diseaseUAB Medicine, June 25, 2015
7Pregnancy safer for women with lupus than previously thoughtNYU Langone Medical Center, June 25, 2015
8Why Lyme disease becomes chronic: New insight could lead to better treatmentsAmerican Society for Microbiology News, June 25, 2015
9Vitamin K - new research shows that this 'forgotten' vitamin may be good for your bone healthInternational Osteoporosis Foundation News, June 24, 2015
10New taxonomy classifies rare genetic bone disorders by metabolic pathogenesisInternational Osteoporosis Foundation News, June 24, 2015

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Sclerostin associated with bone turnover in elderly women

As reported in the Journal of American Geriatrics Society, sclerostin levels are associated with osteocalcin, C-termial telopeptide of type I collagen, and PTH levels in elderly women (≥ 70 y) in nursing homes, but not mortality.

Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients

As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).

Metacarpal DXR-BMD predicts 1-y RA progression

As reported in the Annals of Rheumatic Diseases, a metacarpal BMD determination after 4 months of anti-RA treatment is an independent predictor of 1-y progression in patients without baseline bone erosions (OR=2.0). For patients with baseline erosions, early metacarpal BMD loss is predictive of 1-y progression (OR=1.5).

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Clinical Pearls

Clinical Pearl from Smartest DocImaging in the diagnosis of large-vessel vasculitides.

Clinical Pearl from Smartest DocThe relation of vitiligo/non-segmental vitiligo to Koebner's phenomenon is variably appreciated.

Clinical Pearl from Smartest DocLeukopenia, which may contribute to severe infection, is common but not persistent in many cases of SLE.

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