Sclerostin associated with bone turnover in elderly women
As reported in the Journal of American Geriatrics Society, sclerostin levels are associated with osteocalcin, C-termial telopeptide of type I collagen, and PTH levels in elderly women (≥ 70 y) in nursing homes, but not mortality.
Fluvastatin improves pro-inflammatory and pro-thrombotic markers in aPL-positive patients
As reported in the Annals of Rheumatic Diseases, treatment of persistent aPL-positive patients with fluvastatin (40 mg qd x 3 months) improved pro-inflammatory and pro-thrombotic markers (IL1-β, VEGF, TNF-α, IP10, sCD40L, and sTF).
Increased prevalence of osteoporosis in morbidly obese
As reported in the International Journal of Clinical Practice, while there is a decreased prevalence of osteoporosis up to a BMI of 40 kg/m2, the prevalence of osteoporosis increases in patients with a BMI > 40 kg/m2, which is thought to be due to decreased weight-bearing exercise.