1ERAP1 gene expression is influenced by non-synonymous polymorphisms associated with predisposition to spondyloarthritisArthritis & Rheumatism  Clinical Article
2Procoagulant microparticles are increased in patients with Behçet's disease but do not define a specific subset of clinical manifestationsClinical Rheumatology  Clinical Article
3Risk of falls in patients with ankylosing spondylitisJCR: Journal of Clinical Rheumatology  Clinical Article
4Hyperuricemia, gout, and cardiovascular disease: An updateCurrent Rheumatology Reports  Clinical Article
5Treatment with belimumab restores B cell subsets and their expression of B cell activating factor receptor in patients with primary Sjogren's syndromeRheumatology  Clinical Article
6Dietary patterns and risk of hip fractures in postmenopausal women and men over 50 yearsOsteoporosis International  Clinical Article
7Cortical thinning and progressive cortical porosity in female patients with systemic lupus erythematosus on long-term glucocorticoids: A 2-year case-control studyOsteoporosis International  Clinical Article
8Hospitalization rates and utilization among patients with giant cell arteritis: A population-based study from 1987 to 2012Seminars in Arthritis and Rheumatism  Clinical Article
9Effectiveness, tolerability, and safety of subcutaneous methotrexate in early rheumatoid arthritis: A retrospective analysis of real-world data from the St. Gallen cohortSeminars in Arthritis and Rheumatism  Clinical Article
10More than just minutes of stiffness in the morning: Report from the OMERACT rheumatoid arthritis flare group stiffness breakout sessionsThe Journal of Rheumatology  Clinical Article
1Scientists discover robust evidence that chronic fatigue syndrome is a biological illnessColumbia University's Mailman School of Public Health News
2Antifreeze protein from ticks fights frostbite in miceYale School of Medicine News
3Million man study examines long-term effects of blocking inflammationUniversity of Cambridge News
4Prescription opioid analgesic use among adults: United States, 1999–2012U.S. National Center for Health Statistics News
5The ACR/ARHP Annual Meeting: New directions for goutThe Rheumatologist
6The ACR/ARHP Annual Meeting: Alive and growingThe Rheumatologist
7The ACR/ARHP Annual Meeting: Fibrotic complications of sclerodermaThe Rheumatologist
8The ACR/ARHP Annual Meeting: Diagnosing PACNS and its mimicsThe Rheumatologist
9The ACR/ARHP Annual Meeting: Psoriatic arthritisThe Rheumatologist
10The ACR/ARHP Annual Meeting: Biomarker developmentThe Rheumatologist

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Low vitamin D associated with statin-induced myalgia

As reported in Clinical Therapeutics, of 450 patients prescribed high-dose simvastatin (80 mg qd) for dyslipidemia, 11.1% complained of myalgias. The vitamin D level was lower in patients with myalgias than patients without myalgias (26.2 vs. 36.3 ng/mL).

Mortality increased in juvenile-onset SLE

As reported in Rheumatology, juvenile-onset SLE is associated with increased lupus nephritis, hemolytic anemia, and mortality compared to adult-onset SLE.

Increased prevalence of osteoporosis in morbidly obese

As reported in the International Journal of Clinical Practice, while there is a decreased prevalence of osteoporosis up to a BMI of 40 kg/m2, the prevalence of osteoporosis increases in patients with a BMI > 40 kg/m2, which is thought to be due to decreased weight-bearing exercise.

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Clinical Pearl from Smartest DocSystemic sclerosis is associated with an increased prevalence of myocardial infarction, stroke, and peripheral vascular disease.

Clinical Pearl from Smartest DocTocilizumab-related changes in lipoprotein profile were unrelated to disease activity.

Clinical Pearl from Smartest DocSystemic sclerosis is associated with a higher risk of cancer.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List