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Petscavage JM et al. – The authors report a case of a tumoral calcinosis mimicking the appearance of recurrent osteosarcoma of the left femur and tibia in a 29 year–old woman with a history of osteosarcoma and chronic renal failure. Both processes can radiographically and histologically appear similar. Due to loosening of the orthopaedic hardware, these patient underwent surgical revision and biopsy. The authors review the imaging appearances of both entities as well as the underlying mechanism of tumoral calcinosis secondary to renal disease. The authors also discuss how PET and CT imaging can aid in differentiation of these processes and possibly present surgical biopsy in other cases.



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