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Using Cerebral White Matter for Estimation of Nondisplaceable Binding of 5-HT1A Receptors in Temporal Lobe Epilepsy
The Journal of Nuclear Medicine, 11/03/09

Giovacchini G et al. – Cerebral white matter can be used for the quantification of nondisplaceable binding of 5–HT1A without loss of statistical power for detection of regional group differences. The ROI approach is a good compromise between computational complexity and sensitivity to spillover of activity, and it appears suitable to studies in which PVC is not performed. For 18F–FCWAY, this approach has the advantage of avoiding spillover of 18F–fluoride activity onto the reference region.

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