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Saggiorato E et al. – Semiquantitative 99mTc–MIBI scintigraphy is an adjunctive method to predict preoperatively the malignant behavior of nononcocytic follicular thyroid nodules indeterminate at fine–needle aspiration biopsy, with a potential impact on the definition of their clinical management. Moreover, the good correlation found between immunohistochemical apical expression of MRP1 and the scintigraphic findings supports the 99mTc–MIBI results and provides tissue information on the molecular mechanisms responsible for 99mTc–MIBI images in thyroid lesions.


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