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Dosimetry of 90Y-Ibritumomab Tiuxetan as Consolidation of First Remission in Advanced-Stage Follicular Lymphoma: Results from the International Phase 3 First-Line Indolent Trial
The Journal of Nuclear Medicine, 11/02/09
Delaloye AB et al. – In patients with low or minimal residual tumor burden after first–line chemotherapy of advanced FL, whole–body and bone marrow exposure after 90Y–ibritumomab tiuxetan consolidation showed a significant positive correlation with progression–free survival, whereas dosimetric data could not predict hematologic toxicity.
Angelika Bischof Delaloye , 11/10/09
| Whole-body or bone marrow does and PFS correlated negatively with body weight, suggesting that patients in PR or CR with weight exceeding 80 kg might not receive an adequate radiation dose by the arbitrarily determined maximal activity of 1184 MBq. |
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