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Your Article Summary
Site-specific addition of an 18F-N-methylaminooxy-containing prosthetic group to a vinylsulfone modified peptide
Journal of Labelled Compounds and Radiopharmaceuticals, 10/09/09
Olberg DE et al. – The conjugation yields were studied with respect to reaction time, level of radioactivity, peptide concentration and purity of the [18F]prosthetic group used in the conjugation reaction. Incubation at 70°C gave conjugation yields of around 80% with high radiochemical purity after 70 min at pH 5 in acetate buffer.
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