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Dalen BMV et al. – Untwisting rate from peak systolic twist to MVO was negatively correlated with the E/A ratio. Peak diastolic untwisting velocity and untwisting rate from peak systolic twist to MVO were increased in mild but decreased in moderate and severe diastolic dysfunction compared with control subjects. LV untwisting is delayed in HCM, which probably significantly contributes to diastolic dysfunction.

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