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See Latest ArticlesQuantitative Studies of Bone Using 99mTc-Methylene Diphosphonate Skeletal Plasma Clearance
Seminars in Nuclear Medicine, 10/14/09
Blake GM et al. – Unlike the first 2 methods, the Patlak plot can also be used to measure regional values of Kbone for any chosen ROI. Initial studies have shown good agreement between the 3 methods of measuring Kbone, and highly significant correlations between the change in Kbone values during treatment and the corresponding changes in serum and urinary measurements of biochemical markers of bone formation and bone resorption.
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