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Lemoine L et al. – [18F]F15599 is a radiofluorinated agonist presenting interesting characteristics for probing in vitro and in vivo the high–affinity states of the 5–HT1A receptors. Its differential labelling of 5–HT1A receptors in vitro and in vivo may result from its reported preferential interaction with receptors coupled to specific G–protein subtypes.

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