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Sensorimotor network rewiring in mild cognitive impairment and Alzheimers disease
Human Brain Mapping, 09/30/09
Agosta F et al. – Altered fMRI activations and connections were correlated with the hippocampal atrophy in aMCI and with the overall GM microstructural damage in AD. Motor–associated functional cortical changes in aMCI and AD mirror fMRI changes of the cognitive network, suggesting the occurrence of a widespread brain rewiring with increasing structural damage rather than a specific response of cognitive network.
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