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Watanabe A et al. – dGEMRIC may be a useful method to monitor glycosaminoglycan concentration in patients with RPD following conservative treatment.

Methods

3 groups of knees evaluated
Group I, 35 knees from both knees of patients with bilateral RPD and dislocated side knees of patients with unilateral RPD
Group II, 15 non-dislocated side knees of patients with unilateral RPD
Group III, 20 knees from both knees of healthy volunteers [T1
Differences in post-contrast T1 [T1(Gd)] of cartilage at both medial and lateral facets between groups I, II and III analyzed
Length of time between the initial dislocation and MRI and the total number of dislocations between the initial dislocation and MRI for both medial and lateral facets

Results

mMean T1(Gd) of cartilage at medial facets for groups I, II and III were 411 ± 46 ms, 465 ± 38 ms and 490 ± 29 ms, respectively
Mean T1(Gd) of cartilage at lateral facets for groups I, II and III were 426 ± 53 ms, 466 ± 45 ms and 510 ± 36 ms, respectively
Significant correlations were observed between T1(Gd) of cartilage for both medial and lateral facets and length of time between the initial dislocation and MRI
No other significant correlations

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