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Quantitative Assessment of 99mTc-Depreotide Uptake in Patients with Non-Small-Cell Lung Cancer: Immunohistochemical Correlations
Acta Radiologica, 09/17/09
Herlin G et al. – There is an expression of SSTRs in NSCLC. The degree of tumor differentiation correlates negatively with SSTR2 measured in vitro and positively with MIB–1 expression in tumor tissue. No correlation was found between 99mTc–depreotide uptake and possible prognostic factors such as MIB–1 and p53 expression in tumor cells in NSCLC. Lastly, no correlation was found between 99mTc–depreotide uptake and tumor grade or SSTR2 expression.
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