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Dolovich MB – Changes in the deposition of inhaled aerosols within the lung related to the presence of disease or resulting from inhalation challenge interventions or inhaled therapies can be visualized with PET and may correlate with clinical outcomes. As well, the amount of an inhaled tracer deposited in various regions of the lung can give an indication of the efficiency of drug delivery and, combined with the regional distribution of the drug within the lung and the rate of drug absorption, estimate clinical efficacy and safety.

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