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Mapping brain morphological and functional conversion patterns in amnestic MCI: a voxel-based MRI and FDG-PET study
European Journal of Nuclear Medicine & Molecular Imaging, 08/10/09
Morbelli S et al. – The discordant topography between atrophy and hypometabolism reported in AD is already present at the aMCI stage. Posterior cingulate–precuneus hypometabolism seemed to be an early sign of memory deficit, whereas hypometabolism in the left temporal cortex marked the conversion to AD.
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