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Phase 1 Study of the Pittsburgh Compound B Derivative 18F-Flutemetamol in Healthy Volunteers and Patients with Probable Alzheimer Disease
The Journal of Nuclear Medicine, 07/20/09
Nelissen N et al. – 18F–flutemetamol uptake can be readily quantified. This phase 1 study warrants further studies to validate this 18F–labeled derivative of PiB as a biomarker for A(beta) amyloidosis.
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11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study : The Lancet Neurology
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