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In vivo cytometry of antigen-specific t cells using 19F MRI
Magnetic Resonance in Medicine, 07/24/09
Srinivas M et al. – Longitudinal 19F MRI over 21 days revealed a dynamic accumulation and clearance of T cells in the lymph node draining the antigen. The apparent T–cell numbers were calculated in the LN from the time–lapse 19F MRI data. The effect of in vivo T–cell division on the 19F MRI cell quantification accuracy was investigated using fluorescence assays.
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