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See Latest ArticlesRetrospective correction for T1-weighting bias in T2 values obtained with various spectroscopic spin-echo acquisition schemes
Magnetic Resonance Imaging , 07/10/09
Fleysher R et al. - The authors analyze the phenomenon for common MRS spin-echo T2 acquisition schemes; propose a general post hoc T1-bias correction for any combination; show that approximate knowledge of T1 is sufficient, since a 20% uncertainty in T1 leads to under 3% bias in T2; and consequently, efficient, precision-optimized short TR spin-echo T2 measurement protocols can be designed and used without risk of accuracy loss. Tables of correction for single-refocusing spin-echo and double refocusing, such as, PRESS acquisitions, are provided.
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