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Fujimura Y et al. - 18F-PBR06 can quantify TSPOs in the healthy human brain using 120 min of image acquisition and concurrent measurements of radioligand in plasma. Although brain activity is likely contaminated with radiometabolites, the percentage contamination is thought to be small, because values of distribution volume are stable during 60–120 min and vary by less than 10%. 18F-PBR06 is a longer-lived and promising alternative to 11C-labeled radioligands to measure TSPOs as a biomarker of inflammation in the brain.

Today in CT/SPECT/PET...keeping you current

X-ray computed tomography of the heart
British Medical Bulletin, 11/30/09

Computed Tomography Fluoroscopic-guided Percutaneous Spinal Interventions in the Management of Spinal Pain
Annals, Academy of Medicine, Singapore, 11/30/09

Multiphasic MDCT Enhancement Pattern of Hepatocellular Carcinoma Smaller Than 3 cm in Diameter: Tumor Size and Cellular Differentiation
American Journal of Roentgenology, 11/30/09

Today in Neuroradiology...keeping you current

Computed Tomography Fluoroscopic-guided Percutaneous Spinal Interventions in the Management of Spinal Pain
Annals, Academy of Medicine, Singapore, 11/30/09

Diffusion-weighted MR neurography of the sacral plexus with unidirectional motion probing gradients
European Radiology, 11/25/09

T2 relaxation time abnormalities in bipolar disorder and schizophrenia
Magnetic Resonance in Medicine, 11/25/09

Today in Nuclear Medicine...keeping you current

Preparation and biodistribution of [125I]Melphalan: a potential radioligand for diagnostic and therapeutic applications
Journal of Labelled Compounds and Radiopharmaceuticals, 11/30/09

Use of perfluoro groups in nucleophilic 18F-fluorination
Journal of Labelled Compounds and Radiopharmaceuticals, 11/30/09

Influence of [2H]-labelled acetic acid as solvent in the synthesis of [2H]-labelled perhexiline
Journal of Labelled Compounds and Radiopharmaceuticals, 11/30/09